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K9 Advantix II 2pk Green Dog 4-10 lbs product detail number 1.0 Watch the latest from Petmeds Watch the latest from Petmeds
At a Glance
  • Repels and kills disease-carrying fleas, ticks, and mosquitoes before they bite
  • Kills all life stages of fleas (eggs, pupae, larvae, and adult fleas) and ticks (Deer ticks, American dog ticks, Brown dog ticks, and Lone Star ticks)
  • Kills 98-100 percent of adult fleas within 12 hours
  • Ends flea life cycle by preventing flea offspring (eggs, pupae, and larvae) from maturing into adult fleas
  • Repels biting flies and kills chewing lice
  • Provides one month of protection against ticks, fleas, mosquitoes, biting flies
  • Waterproof - remains effective following a shampoo treatment, swimming or after exposure to rain or sunlight
K9 Advantix II

K9 Advantix II - Flea & Tick Topical for Dogs

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K9 Advantix II 2pk Green Dog 4-10 lbs product detail number 1.0 Watch the latest from Petmeds Watch the latest from Petmeds

* Recommended by our Veterinarian Advisory Board

At a Glance
  • Repels and kills disease-carrying fleas, ticks, and mosquitoes before they bite
  • Kills all life stages of fleas (eggs, pupae, larvae, and adult fleas) and ticks (Deer ticks, American dog ticks, Brown dog ticks, and Lone Star ticks)
  • Kills 98-100 percent of adult fleas within 12 hours
  • Ends flea life cycle by preventing flea offspring (eggs, pupae, and larvae) from maturing into adult fleas
  • Repels biting flies and kills chewing lice
  • Provides one month of protection against ticks, fleas, mosquitoes, biting flies
  • Waterproof - remains effective following a shampoo treatment, swimming or after exposure to rain or sunlight
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About this product
1. Do You Need a Prescription for K9 Advantix II?
Answer
Prescriptions are a mandate when there is an administration of medicine to the drugs. These drugs are often controlled by the FDA. The absence of any medicine that will be ingested by the pets makes them be out of the purview of the FDA. Therefore the prescriptions are not needed for the superficial treatment of fleas ticks and mosquitoes by the use of K9 Advantix II for Dogs. However, an important aspect to note is if the ticks infestation is too high, it often can lead to tick fever. During such situations, you must contact your pet’s vet immediately to administer the right medications along with this tick and flea treatment.
2. Is K9 Advantix II Safe for Dogs?
Answer
K9 Advantix II for Dogs is completely safe to use for your pets at home. You can start using the product among dogs that are over 7 weeks of age. Although it is a non-harmful drug that kills fleas ticks, special care must be taken while administering the drug to the younger pups as well as to the aging dogs that are at a weakening stage due to their age. Till forty-eight hours of administration of K9 Advantix II for Dogs, do not give your pets a bath or shampoo them. This will help increase the efficacy of the product and help you achieve the maximum coverage and help get rid of the majority of the infestations.
3. What Is the Safest Flea and Tick Treatment for Dogs?
Answer
The use of chemical agents to treat fleas or ticks that can cause harm to pets is not recommended. Such usage can often be harmful to your pet and can lead to toxicity. If you are to opt for one that has chemicals to treat the flea or tick control as an additional aid with your existing ones, be sure to use the less toxic ones. A good idea can be to check the details of the ingredients on the product label which gives all the necessary information. As per Natural Resources Defense Council or NRDC, in case there is a need for additional treatment for the infestations by the fleas and ticks with the use of chemical products, s-methoprene or pyriproxyfen are recommended. The reason being these are less toxic ingredients. You can check the label for such products too, as often it is found that manufacturers club other harmful or toxic ingredients with these.
4. How Long After Applying K9 Advantix Can I Touch My Dog?
Answer
The action of K9 Advantix II for Dogs stays for forty-eight hours. So touching your furry friends can happen only after this period. In ideal scenarios, most manufacturers often recommend touching the pets only after the product applied to their body dries out. You should wait till that time when such a period passes. You can also keep track of the pests that fall off your pet post administration of K9 Advantix II for Dogs.
5. What Happens if Dog Licks Advantix?
Answer
Often it happens that the pets can lick the areas that have been applied with the K9 Advantix II for Dogs or they can scratch those areas with their feet and lick them later. In such cases, there are chances that your pet can start to salivate due to the bitter taste of the product, foam can also form in the mouth. They can also start to vomit or nauseate because of the same.
6. How Often Should I Use Advantix on My Dog?
Answer
K9 Advantix II remains effective for four weeks after each application. However, if your dog has severe infections they may need the administration of K9 Advantix in more than one scenario in the same month. But make sure not to apply this more than once every seven days. Once you see that the fleas are controlled, you can return to the normal monthly dosage.
7. Is Advantix Toxic to Dogs?
Answer
K9 Advantix II for Dogs has been supported by the United States Environment Protection Agency. There are no cases of toxicity that have been reported against the usage of K9 Advantix II for Dogs. This is the reason that the veterinarians recommend the use of this shampoo to get rid of the ticks or flea infestation among the dogs. Pet owners also trust this product for the treatment of their pets and keep them away from any harmful chemicals that are mostly found in the commercially available products in the market that help serve the same purpose, either in the form of ingestible or superficial applicators.
8. Can I use K9 Advantix II on my elderly dog?
Answer
The answer to this relative and you should consult with your veterinarian before using any medication on your elderly dog, including K9 Advantix II. This is because older dogs may have health issues or take medications that could interact with K9 Advantix II, potentially causing harmful side effects. Additionally, K9 Advantix II is designed for dogs of a certain weight range and age, so it's vital to ensure that your dog falls within the appropriate parameters for the medication.
9. Is K9 Advantix II waterproof?
Answer
Yes, K9 Advantix II is waterproof once it has been applied and absorbed into the skin. This means that your dog can be bathed or swim after the product has had a chance to dry, typically within 24 hours of application. However, it's important to note that excessive bathing or swimming may decrease the product's effectiveness, so it's generally recommended to avoid bathing your dog more than once a week and to wait at least 48 hours after application before allowing your dog to swim or bathe.
10. How long does K9 Advantix II last?
Answer
K9 Advantix II provides protection against fleas, ticks, and other parasites for up to one month (30 days) after application. However, the period of time the product is effective might vary based on factors like your dog's activity level, exposure to water or bathing, and the severity of the flea and tick infestation in your area.
11. Can I use K9 Advantix II on my dog with sensitive skin?
Answer
K9 Advantix II is not recommended for use on dogs with sensitive skin. While it is generally considered safe and effective for most dogs, dogs with sensitive skin may be more prone to developing skin irritation or other adverse reactions to the medication. Your veterinarian can evaluate your dog's skin health and recommend a flea and tick medication that is less likely to cause irritation or other adverse reactions.
12. How does K9 Advantix II compare to other flea and tick treatments?
Answer
K9 Advantix II has the benefit of being waterproof, allowing dogs to swim or take a bath without having the drug lose its potency. Even pups as young as 7 weeks old can utilize it without concern. Also, K9 Advantix II provides broad-spectrum defense against a variety of parasites, including mosquitoes and biting flies, in comparison to other flea and tick medications, which may be crucial if you reside in a region where these pests are common. For dogs with sensitive skin or those who are prone to skin irritations or other unfavorable reactions to flea and tick treatments, it might not be the ideal option.
13. Can I use K9 Advantix II on dogs with medical conditions?
Answer
Yes, however before taking K9 Advantix II or any other flea and tick medicine, it's essential to speak with your veterinarian. Some medical conditions or medications may interact with K9 Advantix II or other flea and tick medications, potentially causing adverse reactions or reducing the effectiveness of the medication.
14. Can K9 Advantix II be used with other medications?
Answer
It is important to consult with your veterinarian before using K9 Advantix II with other medications, as some drugs may interact with imidacloprid and permethrin, the active ingredients in K9 Advantix II. Certain medications may increase the risk of adverse reactions or reduce the effectiveness of the medication, so you should disclose all medications and supplements that your dog is currently taking to your veterinarian. Additionally, K9 Advantix II should not be used on dogs that are currently taking other flea and tick medications without first consulting with a veterinarian.
15. Is K9 Advantix II effective against all types of fleas?
Answer
K9 Advantix II is effective against several species of fleas, including the common cat flea (Ctenocephalides felis) and the dog flea (Ctenocephalides canis). These fleas are the most common species found on dogs and are responsible for causing itching, scratching, and other skin irritations. K9 Advantix II is designed to kill fleas on contact, as well as to repel new fleas from infesting your dog for up to 4 weeks after application.
16. Does K9 Advantix II work to prevent mosquitoes?
Answer
Yes, in addition to fleas, ticks, and other parasites, K9 Advantix II is effective against mosquitoes. Imidacloprid and permethrin, the two active components in K9 Advantix II, combine to both repel and kill mosquitoes on contact.
17. Does K9 Advantix II eradicate heartworms?
Answer
K9 Advantix II is not an effective treatment for heartworms. K9 Advantix II is made to guard against fleas, ticks, mosquitoes, and other biting flies, but it does not destroy heartworms. Heartworm illness is brought on by a parasitic worm that is spread by mosquitoes.
18. How do I dispose of empty K9 Advantix II tubes?
Answer
To dispose of empty K9 Advantix II tubes, empty the contents of the tube onto your dog's skin as directed, and allow it to dry completely before recapping it. Place the capped tube in a plastic bag, seal the bag, and discard it in your household trash. Do not reuse empty K9 Advantix II tubes, and do not pour unused products down the drain or toilet.

What is K9 Advantix II?

K9 Advantix II is a monthly preventative for dogs that offers comprehensive protection against ticks, fleas, mosquitoes, biting flies, and chewing lice. K9 Advantix II is a top veterinarian-recommended brand because it repels and kills all life stages of fleas (eggs, pupae, larvae, and adult fleas) and ticks (Deer ticks, American dog ticks, Brown dog ticks, and Lone Star ticks). K9 Advantix II kills 98-100 percent of fleas within 12 hours and continues working for one month to prevent infestations. Fleas and ticks are killed on contact with a treated dog, which means that fleas don't have to bite and ticks don't have to attach to die. This helps prevent transmission of flea-borne and tick-borne diseases such as tapeworms, Lyme disease, tick paralysis, ehrlichia, and Rocky Mountain spotted fever. Killing fleas before they bite may also help prevent skin allergies caused by flea saliva. As well, K9 Advantix II repels mosquitoes before they bite, which may help prevent transmission of heartworms. K9 Advantix II protects your pet before parasites have a chance to bite, not after.

For:

Dogs and Puppies (7+ weeks of age, weighing 4+ lbs)

Benefits:

  • Repels and kills disease-carrying fleas, ticks, and mosquitoes before they bite
  • Kills all life stages of fleas (eggs, pupae, larvae, and adult fleas) and ticks (Deer ticks, American dog ticks, Brown dog ticks, and Lone Star ticks)
  • Kills 98-100 percent of adult fleas within 12 hours
  • Ends flea life cycle by preventing flea offspring (eggs, pupae, and larvae) from maturing into adult fleas
  • Repels biting flies and kills chewing lice
  • Provides one month of protection against ticks, fleas, mosquitoes, biting flies
  • Waterproof - remains effective following a shampoo treatment, swimming or after exposure to rain or sunlight

How does K9 Advantix II work?

K9 Advantix II combines imidacloprid and permethrin to repel and kill fleas, ticks, and mosquitoes. Both ingredients work on contact, attacking parasite nerve cells at different sites. Together these ingredients overwhelm the nervous system killing the parasite. Pyriproxyfen is an insect growth regulator. K9 Advantix II topical solution also repels biting flies and kills lice.

Cautions:

DO NOT USE ON CATS. Cats cannot metabolize the ingredients used in this product. Cats must be separated from dogs during treatment. Do not allow your cat to come in contact with a treated dog for 24 hours. Some small and medium dogs may have an adverse skin reaction.

Brand Name:

K9 Advantix II (Elanco)

What is the most important thing I should know about K9 Advantix II?

The active ingredients in K9 Advantix II are Imidacloprid (8.8%), Permethrin (44.0%), and Pyriproxyfen (0.44%). K9 Advantix II is for use on dogs and puppies weighing 4 lbs or more and 7 weeks of age or older. It is used for the topical prevention and treatment of ticks, fleas, mosquitoes, biting flies, and chewing lice on dogs. K9 Advantix II repels and kills ticks including deer ticks (the major carrier of Lyme disease), American dog ticks, Brown dog ticks and lone star ticks. Additionally, K9 Advantix II repels and kills all life stages of fleas, repels and kills mosquitoes, kills chewing lice, and repels biting flies. K9 Advantix II is a non-prescription (OTC) product available as 0.014 fl oz (0.4 ml) applicators for dogs 4-10 lbs (Green), 0.034 fl oz (1.0 ml) applicators for dogs 11-20 lbs (Teal), 0.084 fl oz (2.5 ml) applicators for dogs 21-55 lbs (Red), and 0.135 fl oz (4.0 ml) applicators for dogs over 55 lbs (Blue).

What should I discuss with my veterinarian before giving K9 Advantix II to my pet?

Consult a veterinarian before using on medicated animals and debilitated, aged, pregnant or nursing animals.

How should K9 Advantix II be applied?

For use only on dogs. Do not use on cats or on other animals. Have your dog stand for easy application. Part the hair on your dog's back between the shoulder blades, until the skin is visible. For dogs up to 20 lbs, apply the entire contents of the applicator tube to 2 or 3 spots on the top of the back from the shoulder to the base of the tail. For dogs 21 lbs and over, apply the entire contents of the applicator tube to 4 or 6 spots on the top of the back from the shoulder to the base of the tail. If your household has cats or other pets, separate them from the treated dog for 24 hours.

What are the potential side effects of K9 Advantix II?

Monitor your dog after application. Side effects may include signs of skin irritation such as redness, scratching, or other signs of discomfort. Gastrointestinal signs such as vomiting or diarrhea have also been reported. If these or other side effects (such as lethargy or agitation) occur, consult your veterinarian or call 1-800-422-9874. Individual sensitivities, while rare, may occur after using any pesticide product for pets. A small percentage of dogs have had adverse reactions to K9 Advantix II. A sensation of burning, tingling, itching, redness or numbness of the skin may occur after topical application. This sensation usually begins 1-2 hours after application. In addition, reactions have occurred in cats that have been exposed to a medicated dog. That is why it is important to separate your cat from a medicated dog for 24 hours. Elanco, the manufacturer of K9 Advantix II, indicates that some of these symptoms will dissipate within 48 hours; however, if your pet is experiencing adverse reactions, please complete the following steps:

  • Stop applying the medication
  • Wash your dog with a detergent based soap (Dawn or Palmolive dish detergents work best). Do not scrub the affected area, as this may cause more skin irritation. Please note: This process is applicable for both dogs and cats.
  • Call your veterinarian
  • Call Elanco Emergency Support Line at 1-800-422-9874. Let Elanco know your dog is having an adverse reaction to K9 Advantix by calling 1-800-422-9874. This line is staffed 24 hours a day, 7 days a week.

What happens if I miss giving a dose of K9 Advantix II?

If you miss a dose, apply the next dose as soon as possible and resume a monthly schedule.

What happens if I overdose my pet on K9 Advantix II?

Contact your veterinarian or veterinary emergency room.

What should I avoid while giving K9 Advantix II to my pet?

This product is for external use only on dogs and puppies 4 lbs or more and 7 weeks or older. Do not get this product in your dog's eyes or mouth. Do not use this product on animals other than dogs. In households with cats, separate the treated dog for about 24 hours. Due to their unique physiology and inability to metabolize certain compounds, this product must not be used on cats. If applied to a cat, or ingested by a cat which actively grooms a recently treated dog, this product may have serious harmful effects. If this occurs, contact your veterinarian immediately. It is important to apply this product no more than once a month and to use the correct strength for the weight of the dog. This product is harmful to humans if swallowed. Call a physician or poison control center for advice. Have the patient sip water. Do not induce vomiting unless advised to and the patient is conscious. This product can cause substantial but temporary eye injury. Do not get in eyes or on skin or clothing. Wash thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco or using the toilet. Remove and wash contaminated clothing before reuse..

What other drugs will affect K9 Advantix II?

If your pet is on medication, consult your veterinarian before using this or any other product.

See more

K9 Advantix II Directions:

HOW TO OPEN

  1. Be sure the tube is at the bottom of the pouch.
  2. Using scissors, cut the pouch across the top and remove the tube.

HOW TO APPLY

  1. Use only on Dogs. DO NOT USE ON CATS or other animals.
  2. Do not apply to dogs weighing less than 4 lbs.
  3. Remove the applicator tube from the package. Use scissors to peel down foil.
  4. Hold the applicator tube in an upright position. Pull the cap off the tube.
  5. Turn the cap around and place the other end of the cap back on the tube.
  6. Your dog should be standing for easy application. Evenly apply the entire contents of the K9 Advantix II tube to two or three spots on the top of the back from the shoulder to the base of the tail. At each spot, part the hair until the skin is visible. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin. Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of your dog. Do not get this product in your dog's eyes or allow your dog to ingest this product.
  7. Discard the empty tube as described in Storage and Disposal.
  8. In cases of severe pest infestations, retreatment is allowable earlier than four (4) weeks. Do not retreat more of often than once every seven (7) days. After pest control is attained, return to a monthly retreatment schedule.
Tip:

In households with cats, separate the treated dog for 24 hours until the product is thoroughly dry.

K9 Advantix II Dosage for Dogs:

Dogs/Puppies (7+ weeks of age, weighing 4+ lbs):
Weight Amount
1-3 lbs Do not use
4-10 lbs Apply contents of 1 applicator once a month (Green Box)
11-20 lbs Apply contents of 1 applicator once a month (Teal Box)
21-55 lbs Apply contents of 1 applicator once a month (Red Box)
Over 55 lbs Apply contents of 1 applicator once a month (Blue Box)
K9 Advantix II Dosage for Cats:
Cats
Do not use!
K9 Advantix II Dosage for Horses:
Horses
Do not use!

Storage:

Do not contaminate water, food or feed by storage or disposal.

Environmental Hazards:

This product is extremely toxic to aquatic organisms, including fish and invertebrates. Do not add directly to water. Do not contaminate water when disposing of product or packaging.

Pesticide Storage:

Store K9 Advantix II in a cool, dry place. Protect from freezing.

Pesticide Disposal and Container Handling:

Nonrefillable container.

If empty:

Do not reuse this container. Place in trash or offer for recycling, if available.

If partly filled:

Call your local solid waste agency or 1-800-422-9874 for disposal instructions. Never place unused product down any indoor or outdoor drain.

Do not refrigerate. Store in the original container only. Do not reu

K9 Advantix II Ingredients:

K9 Advantix II for Dogs 4-10 lbs (Small Dog - Green Box) (0.4 ml):
Active Ingredients (per applicator tube) % By Weight
Imidacloprid 8.80%
Permethrin* 44.0%
Pyriproxyfen 0.44%
Other Ingredients (not specified) 46.76%
*cis/trans ratio: Max 55% (+/-) cis and min 45% (+/-) trans
K9 Advantix II for Dogs 11-20 lbs (Medium Dog - Teal Box) (1.0 ml):
Active Ingredients (per applicator tube) % By Weight
Imidacloprid 8.80%
Permethrin* 44.0%
Pyriproxyfen 0.44%
Other Ingredients (not specified) 46.76%
*cis/trans ratio: Max 55% (+/-) cis and min 45% (+/-) trans
K9 Advantix II for Dogs 21-55 lbs (Large Dog - Red Box) (2.5 ml):
Active Ingredients (per applicator tube) % By Weight
Imidacloprid 8.80%
Permethrin* 44.0%
Pyriproxyfen 0.44%
Other Ingredients (not specified) 46.76%
*cis/trans ratio: Max 55% (+/-) cis and min 45% (+/-) trans
K9 Advantix II for Dogs over 55 lbs (Extra Large Dog - Blue Box) (4.0 ml):
Active Ingredients (per applicator tube) % By Weight
Imidacloprid 8.80%
Permethrin* 44.0%
Pyriproxyfen 0.44%
Other Ingredients (not specified) 46.76%
*cis/trans ratio: Max 55% (+/-) cis and min 45% (+/-) trans
Product Details
plus minus

What is K9 Advantix II?

K9 Advantix II is a monthly preventative for dogs that offers comprehensive protection against ticks, fleas, mosquitoes, biting flies, and chewing lice. K9 Advantix II is a top veterinarian-recommended brand because it repels and kills all life stages of fleas (eggs, pupae, larvae, and adult fleas) and ticks (Deer ticks, American dog ticks, Brown dog ticks, and Lone Star ticks). K9 Advantix II kills 98-100 percent of fleas within 12 hours and continues working for one month to prevent infestations. Fleas and ticks are killed on contact with a treated dog, which means that fleas don't have to bite and ticks don't have to attach to die. This helps prevent transmission of flea-borne and tick-borne diseases such as tapeworms, Lyme disease, tick paralysis, ehrlichia, and Rocky Mountain spotted fever. Killing fleas before they bite may also help prevent skin allergies caused by flea saliva. As well, K9 Advantix II repels mosquitoes before they bite, which may help prevent transmission of heartworms. K9 Advantix II protects your pet before parasites have a chance to bite, not after.

For:

Dogs and Puppies (7+ weeks of age, weighing 4+ lbs)

Benefits:

  • Repels and kills disease-carrying fleas, ticks, and mosquitoes before they bite
  • Kills all life stages of fleas (eggs, pupae, larvae, and adult fleas) and ticks (Deer ticks, American dog ticks, Brown dog ticks, and Lone Star ticks)
  • Kills 98-100 percent of adult fleas within 12 hours
  • Ends flea life cycle by preventing flea offspring (eggs, pupae, and larvae) from maturing into adult fleas
  • Repels biting flies and kills chewing lice
  • Provides one month of protection against ticks, fleas, mosquitoes, biting flies
  • Waterproof - remains effective following a shampoo treatment, swimming or after exposure to rain or sunlight

How does K9 Advantix II work?

K9 Advantix II combines imidacloprid and permethrin to repel and kill fleas, ticks, and mosquitoes. Both ingredients work on contact, attacking parasite nerve cells at different sites. Together these ingredients overwhelm the nervous system killing the parasite. Pyriproxyfen is an insect growth regulator. K9 Advantix II topical solution also repels biting flies and kills lice.

Cautions:

DO NOT USE ON CATS. Cats cannot metabolize the ingredients used in this product. Cats must be separated from dogs during treatment. Do not allow your cat to come in contact with a treated dog for 24 hours. Some small and medium dogs may have an adverse skin reaction.

Brand Name:

K9 Advantix II (Elanco)

What is the most important thing I should know about K9 Advantix II?

The active ingredients in K9 Advantix II are Imidacloprid (8.8%), Permethrin (44.0%), and Pyriproxyfen (0.44%). K9 Advantix II is for use on dogs and puppies weighing 4 lbs or more and 7 weeks of age or older. It is used for the topical prevention and treatment of ticks, fleas, mosquitoes, biting flies, and chewing lice on dogs. K9 Advantix II repels and kills ticks including deer ticks (the major carrier of Lyme disease), American dog ticks, Brown dog ticks and lone star ticks. Additionally, K9 Advantix II repels and kills all life stages of fleas, repels and kills mosquitoes, kills chewing lice, and repels biting flies. K9 Advantix II is a non-prescription (OTC) product available as 0.014 fl oz (0.4 ml) applicators for dogs 4-10 lbs (Green), 0.034 fl oz (1.0 ml) applicators for dogs 11-20 lbs (Teal), 0.084 fl oz (2.5 ml) applicators for dogs 21-55 lbs (Red), and 0.135 fl oz (4.0 ml) applicators for dogs over 55 lbs (Blue).

What should I discuss with my veterinarian before giving K9 Advantix II to my pet?

Consult a veterinarian before using on medicated animals and debilitated, aged, pregnant or nursing animals.

How should K9 Advantix II be applied?

For use only on dogs. Do not use on cats or on other animals. Have your dog stand for easy application. Part the hair on your dog's back between the shoulder blades, until the skin is visible. For dogs up to 20 lbs, apply the entire contents of the applicator tube to 2 or 3 spots on the top of the back from the shoulder to the base of the tail. For dogs 21 lbs and over, apply the entire contents of the applicator tube to 4 or 6 spots on the top of the back from the shoulder to the base of the tail. If your household has cats or other pets, separate them from the treated dog for 24 hours.

What are the potential side effects of K9 Advantix II?

Monitor your dog after application. Side effects may include signs of skin irritation such as redness, scratching, or other signs of discomfort. Gastrointestinal signs such as vomiting or diarrhea have also been reported. If these or other side effects (such as lethargy or agitation) occur, consult your veterinarian or call 1-800-422-9874. Individual sensitivities, while rare, may occur after using any pesticide product for pets. A small percentage of dogs have had adverse reactions to K9 Advantix II. A sensation of burning, tingling, itching, redness or numbness of the skin may occur after topical application. This sensation usually begins 1-2 hours after application. In addition, reactions have occurred in cats that have been exposed to a medicated dog. That is why it is important to separate your cat from a medicated dog for 24 hours. Elanco, the manufacturer of K9 Advantix II, indicates that some of these symptoms will dissipate within 48 hours; however, if your pet is experiencing adverse reactions, please complete the following steps:

  • Stop applying the medication
  • Wash your dog with a detergent based soap (Dawn or Palmolive dish detergents work best). Do not scrub the affected area, as this may cause more skin irritation. Please note: This process is applicable for both dogs and cats.
  • Call your veterinarian
  • Call Elanco Emergency Support Line at 1-800-422-9874. Let Elanco know your dog is having an adverse reaction to K9 Advantix by calling 1-800-422-9874. This line is staffed 24 hours a day, 7 days a week.

What happens if I miss giving a dose of K9 Advantix II?

If you miss a dose, apply the next dose as soon as possible and resume a monthly schedule.

What happens if I overdose my pet on K9 Advantix II?

Contact your veterinarian or veterinary emergency room.

What should I avoid while giving K9 Advantix II to my pet?

This product is for external use only on dogs and puppies 4 lbs or more and 7 weeks or older. Do not get this product in your dog's eyes or mouth. Do not use this product on animals other than dogs. In households with cats, separate the treated dog for about 24 hours. Due to their unique physiology and inability to metabolize certain compounds, this product must not be used on cats. If applied to a cat, or ingested by a cat which actively grooms a recently treated dog, this product may have serious harmful effects. If this occurs, contact your veterinarian immediately. It is important to apply this product no more than once a month and to use the correct strength for the weight of the dog. This product is harmful to humans if swallowed. Call a physician or poison control center for advice. Have the patient sip water. Do not induce vomiting unless advised to and the patient is conscious. This product can cause substantial but temporary eye injury. Do not get in eyes or on skin or clothing. Wash thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco or using the toilet. Remove and wash contaminated clothing before reuse..

What other drugs will affect K9 Advantix II?

If your pet is on medication, consult your veterinarian before using this or any other product.

See more
How to use
plus minus

K9 Advantix II Directions:

HOW TO OPEN

  1. Be sure the tube is at the bottom of the pouch.
  2. Using scissors, cut the pouch across the top and remove the tube.

HOW TO APPLY

  1. Use only on Dogs. DO NOT USE ON CATS or other animals.
  2. Do not apply to dogs weighing less than 4 lbs.
  3. Remove the applicator tube from the package. Use scissors to peel down foil.
  4. Hold the applicator tube in an upright position. Pull the cap off the tube.
  5. Turn the cap around and place the other end of the cap back on the tube.
  6. Your dog should be standing for easy application. Evenly apply the entire contents of the K9 Advantix II tube to two or three spots on the top of the back from the shoulder to the base of the tail. At each spot, part the hair until the skin is visible. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin. Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of your dog. Do not get this product in your dog's eyes or allow your dog to ingest this product.
  7. Discard the empty tube as described in Storage and Disposal.
  8. In cases of severe pest infestations, retreatment is allowable earlier than four (4) weeks. Do not retreat more of often than once every seven (7) days. After pest control is attained, return to a monthly retreatment schedule.
Tip:

In households with cats, separate the treated dog for 24 hours until the product is thoroughly dry.

K9 Advantix II Dosage for Dogs:

Dogs/Puppies (7+ weeks of age, weighing 4+ lbs):
Weight Amount
1-3 lbs Do not use
4-10 lbs Apply contents of 1 applicator once a month (Green Box)
11-20 lbs Apply contents of 1 applicator once a month (Teal Box)
21-55 lbs Apply contents of 1 applicator once a month (Red Box)
Over 55 lbs Apply contents of 1 applicator once a month (Blue Box)
K9 Advantix II Dosage for Cats:
Cats
Do not use!
K9 Advantix II Dosage for Horses:
Horses
Do not use!

Storage:

Do not contaminate water, food or feed by storage or disposal.

Environmental Hazards:

This product is extremely toxic to aquatic organisms, including fish and invertebrates. Do not add directly to water. Do not contaminate water when disposing of product or packaging.

Pesticide Storage:

Store K9 Advantix II in a cool, dry place. Protect from freezing.

Pesticide Disposal and Container Handling:

Nonrefillable container.

If empty:

Do not reuse this container. Place in trash or offer for recycling, if available.

If partly filled:

Call your local solid waste agency or 1-800-422-9874 for disposal instructions. Never place unused product down any indoor or outdoor drain.

Do not refrigerate. Store in the original container only. Do not reu

Ingredients
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K9 Advantix II Ingredients:

K9 Advantix II for Dogs 4-10 lbs (Small Dog - Green Box) (0.4 ml):
Active Ingredients (per applicator tube) % By Weight
Imidacloprid 8.80%
Permethrin* 44.0%
Pyriproxyfen 0.44%
Other Ingredients (not specified) 46.76%
*cis/trans ratio: Max 55% (+/-) cis and min 45% (+/-) trans
K9 Advantix II for Dogs 11-20 lbs (Medium Dog - Teal Box) (1.0 ml):
Active Ingredients (per applicator tube) % By Weight
Imidacloprid 8.80%
Permethrin* 44.0%
Pyriproxyfen 0.44%
Other Ingredients (not specified) 46.76%
*cis/trans ratio: Max 55% (+/-) cis and min 45% (+/-) trans
K9 Advantix II for Dogs 21-55 lbs (Large Dog - Red Box) (2.5 ml):
Active Ingredients (per applicator tube) % By Weight
Imidacloprid 8.80%
Permethrin* 44.0%
Pyriproxyfen 0.44%
Other Ingredients (not specified) 46.76%
*cis/trans ratio: Max 55% (+/-) cis and min 45% (+/-) trans
K9 Advantix II for Dogs over 55 lbs (Extra Large Dog - Blue Box) (4.0 ml):
Active Ingredients (per applicator tube) % By Weight
Imidacloprid 8.80%
Permethrin* 44.0%
Pyriproxyfen 0.44%
Other Ingredients (not specified) 46.76%
*cis/trans ratio: Max 55% (+/-) cis and min 45% (+/-) trans
Q&A
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1. Do You Need a Prescription for K9 Advantix II?
Answer
Prescriptions are a mandate when there is an administration of medicine to the drugs. These drugs are often controlled by the FDA. The absence of any medicine that will be ingested by the pets makes them be out of the purview of the FDA. Therefore the prescriptions are not needed for the superficial treatment of fleas ticks and mosquitoes by the use of K9 Advantix II for Dogs. However, an important aspect to note is if the ticks infestation is too high, it often can lead to tick fever. During such situations, you must contact your pet’s vet immediately to administer the right medications along with this tick and flea treatment.
2. Is K9 Advantix II Safe for Dogs?
Answer
K9 Advantix II for Dogs is completely safe to use for your pets at home. You can start using the product among dogs that are over 7 weeks of age. Although it is a non-harmful drug that kills fleas ticks, special care must be taken while administering the drug to the younger pups as well as to the aging dogs that are at a weakening stage due to their age. Till forty-eight hours of administration of K9 Advantix II for Dogs, do not give your pets a bath or shampoo them. This will help increase the efficacy of the product and help you achieve the maximum coverage and help get rid of the majority of the infestations.
3. What Is the Safest Flea and Tick Treatment for Dogs?
Answer
The use of chemical agents to treat fleas or ticks that can cause harm to pets is not recommended. Such usage can often be harmful to your pet and can lead to toxicity. If you are to opt for one that has chemicals to treat the flea or tick control as an additional aid with your existing ones, be sure to use the less toxic ones. A good idea can be to check the details of the ingredients on the product label which gives all the necessary information. As per Natural Resources Defense Council or NRDC, in case there is a need for additional treatment for the infestations by the fleas and ticks with the use of chemical products, s-methoprene or pyriproxyfen are recommended. The reason being these are less toxic ingredients. You can check the label for such products too, as often it is found that manufacturers club other harmful or toxic ingredients with these.
4. How Long After Applying K9 Advantix Can I Touch My Dog?
Answer
The action of K9 Advantix II for Dogs stays for forty-eight hours. So touching your furry friends can happen only after this period. In ideal scenarios, most manufacturers often recommend touching the pets only after the product applied to their body dries out. You should wait till that time when such a period passes. You can also keep track of the pests that fall off your pet post administration of K9 Advantix II for Dogs.
5. What Happens if Dog Licks Advantix?
Answer
Often it happens that the pets can lick the areas that have been applied with the K9 Advantix II for Dogs or they can scratch those areas with their feet and lick them later. In such cases, there are chances that your pet can start to salivate due to the bitter taste of the product, foam can also form in the mouth. They can also start to vomit or nauseate because of the same.
6. How Often Should I Use Advantix on My Dog?
Answer
K9 Advantix II remains effective for four weeks after each application. However, if your dog has severe infections they may need the administration of K9 Advantix in more than one scenario in the same month. But make sure not to apply this more than once every seven days. Once you see that the fleas are controlled, you can return to the normal monthly dosage.
7. Is Advantix Toxic to Dogs?
Answer
K9 Advantix II for Dogs has been supported by the United States Environment Protection Agency. There are no cases of toxicity that have been reported against the usage of K9 Advantix II for Dogs. This is the reason that the veterinarians recommend the use of this shampoo to get rid of the ticks or flea infestation among the dogs. Pet owners also trust this product for the treatment of their pets and keep them away from any harmful chemicals that are mostly found in the commercially available products in the market that help serve the same purpose, either in the form of ingestible or superficial applicators.
8. Can I use K9 Advantix II on my elderly dog?
Answer
The answer to this relative and you should consult with your veterinarian before using any medication on your elderly dog, including K9 Advantix II. This is because older dogs may have health issues or take medications that could interact with K9 Advantix II, potentially causing harmful side effects. Additionally, K9 Advantix II is designed for dogs of a certain weight range and age, so it's vital to ensure that your dog falls within the appropriate parameters for the medication.
9. Is K9 Advantix II waterproof?
Answer
Yes, K9 Advantix II is waterproof once it has been applied and absorbed into the skin. This means that your dog can be bathed or swim after the product has had a chance to dry, typically within 24 hours of application. However, it's important to note that excessive bathing or swimming may decrease the product's effectiveness, so it's generally recommended to avoid bathing your dog more than once a week and to wait at least 48 hours after application before allowing your dog to swim or bathe.
10. How long does K9 Advantix II last?
Answer
K9 Advantix II provides protection against fleas, ticks, and other parasites for up to one month (30 days) after application. However, the period of time the product is effective might vary based on factors like your dog's activity level, exposure to water or bathing, and the severity of the flea and tick infestation in your area.
11. Can I use K9 Advantix II on my dog with sensitive skin?
Answer
K9 Advantix II is not recommended for use on dogs with sensitive skin. While it is generally considered safe and effective for most dogs, dogs with sensitive skin may be more prone to developing skin irritation or other adverse reactions to the medication. Your veterinarian can evaluate your dog's skin health and recommend a flea and tick medication that is less likely to cause irritation or other adverse reactions.
12. How does K9 Advantix II compare to other flea and tick treatments?
Answer
K9 Advantix II has the benefit of being waterproof, allowing dogs to swim or take a bath without having the drug lose its potency. Even pups as young as 7 weeks old can utilize it without concern. Also, K9 Advantix II provides broad-spectrum defense against a variety of parasites, including mosquitoes and biting flies, in comparison to other flea and tick medications, which may be crucial if you reside in a region where these pests are common. For dogs with sensitive skin or those who are prone to skin irritations or other unfavorable reactions to flea and tick treatments, it might not be the ideal option.
13. Can I use K9 Advantix II on dogs with medical conditions?
Answer
Yes, however before taking K9 Advantix II or any other flea and tick medicine, it's essential to speak with your veterinarian. Some medical conditions or medications may interact with K9 Advantix II or other flea and tick medications, potentially causing adverse reactions or reducing the effectiveness of the medication.
14. Can K9 Advantix II be used with other medications?
Answer
It is important to consult with your veterinarian before using K9 Advantix II with other medications, as some drugs may interact with imidacloprid and permethrin, the active ingredients in K9 Advantix II. Certain medications may increase the risk of adverse reactions or reduce the effectiveness of the medication, so you should disclose all medications and supplements that your dog is currently taking to your veterinarian. Additionally, K9 Advantix II should not be used on dogs that are currently taking other flea and tick medications without first consulting with a veterinarian.
15. Is K9 Advantix II effective against all types of fleas?
Answer
K9 Advantix II is effective against several species of fleas, including the common cat flea (Ctenocephalides felis) and the dog flea (Ctenocephalides canis). These fleas are the most common species found on dogs and are responsible for causing itching, scratching, and other skin irritations. K9 Advantix II is designed to kill fleas on contact, as well as to repel new fleas from infesting your dog for up to 4 weeks after application.
16. Does K9 Advantix II work to prevent mosquitoes?
Answer
Yes, in addition to fleas, ticks, and other parasites, K9 Advantix II is effective against mosquitoes. Imidacloprid and permethrin, the two active components in K9 Advantix II, combine to both repel and kill mosquitoes on contact.
17. Does K9 Advantix II eradicate heartworms?
Answer
K9 Advantix II is not an effective treatment for heartworms. K9 Advantix II is made to guard against fleas, ticks, mosquitoes, and other biting flies, but it does not destroy heartworms. Heartworm illness is brought on by a parasitic worm that is spread by mosquitoes.
18. How do I dispose of empty K9 Advantix II tubes?
Answer
To dispose of empty K9 Advantix II tubes, empty the contents of the tube onto your dog's skin as directed, and allow it to dry completely before recapping it. Place the capped tube in a plastic bag, seal the bag, and discard it in your household trash. Do not reuse empty K9 Advantix II tubes, and do not pour unused products down the drain or toilet.
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Marc
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No Fleas
We have 5 dogs, 3 Goldens & 2 Labs...product works great.
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Pamela Simmons
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Great product
We love K9AdvantixII...easy to use, works great. No fleas, ticks or mosquito bites- which means no heartworm risk, or Lyme, or any other associated illnesses! Purchasing through PetCare is the most affordable way to safely protect our dog, and without a reliable, affordable product, Casey wouldn't be able to spend time doing what he loves- spending time with us outdoors!
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