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Nexgard Plus - Flea, Tick, & Broad Spectrum Prevention Chewable Tablet for Dogs 8.1 to 17 lbs. (Green Box) 3 Chews (3 Month Supply) product detail number 1.0 13351 13351 13351 13351 13351 Watch the latest from Petmeds
At a Glance
  • Convenient one-and-done monthly dosing for parasite protection
  • Kills adult fleas before they can lay eggs
  • Kills 4 species of ticks (black-legged ticks, brown dog ticks, American dog ticks, & lone star ticks)
  • Effectively prevents heartworm disease
  • Treats and controls 3 species of hookworms and 2 species of roundworms
  • Tasty, soft beef-flavored chew that’s a delight for your dog
  • Safe for puppies as young as 8 weeks of age
NexGard Plus

NexGard Plus - Flea, Tick, & Broad Spectrum Prevention Chewable Tablet for Dogs

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$135.00
$111.90 See Price in Cart with code CARE25 tooltip Why don't we show the price? Sometimes the manufacturers do not allow us to show our price. Don't worry; you'll be able to see the price in checkout before you decide to buy it.
Prescription Item

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Prescription item

Save $42 by joining PetPlus

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Nexgard Plus - Flea, Tick, & Broad Spectrum Prevention Chewable Tablet for Dogs 8.1 to 17 lbs. (Green Box) 3 Chews (3 Month Supply) product detail number 1.0 13351 13351 13351 13351 13351 Watch the latest from Petmeds
At a Glance
  • Convenient one-and-done monthly dosing for parasite protection
  • Kills adult fleas before they can lay eggs
  • Kills 4 species of ticks (black-legged ticks, brown dog ticks, American dog ticks, & lone star ticks)
  • Effectively prevents heartworm disease
  • Treats and controls 3 species of hookworms and 2 species of roundworms
  • Tasty, soft beef-flavored chew that’s a delight for your dog
  • Safe for puppies as young as 8 weeks of age
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About this product
1. How do I use NexGard® PLUS (afoxaloner, moxidectin, pyrantel chewable tablets) for Dogs?
Answer
NexGard® PLUS (afoxaloner, moxidectin, pyrantel chewable tablets) is used to protect your dog from fleas and ticks, PLUS heartworm disease, roundworms, and hookworms. NexGard PLUS chews are available in a delicious, beef-flavored soft chew that makes monthly dosing a delight for your dogs. For each monthly dose, a chew can be given with or without food. See the product label for full dosing instructions, and always check with your vet regarding their recommendations for your pet.
2. How fast do NexGard® PLUS chews work?
Answer
NexGard® PLUS chews kill fleas fast before they can lay eggs. In a well-controlled laboratory study, afoxolaner alone began to kill fleas 4 hours after initial administration and was >99% effective at 8 hours. NexGard PLUS chews provide powerful protection against fleas and ticks for a full month. NexGard PLUS chews work to prevent heartworm disease by killing any heartworm larvae that were acquired in the previous month. That’s why it is so important for your dog to receive the appropriate dose of NexGard PLUS chews every month, year-round. The pyrantel in NexGard PLUS chews is a dewormer that treats and controls 3 species of hookworms and 2 species of roundworms.
3. Why am I still seeing fleas on my dog after using NexGard® PLUS chewable tablets?
Answer
You are likely seeing NEW fleas on your pet, which are jumping on your dog as it moves through infested areas. These fleas will be killed quickly by NexGard® PLUS chews before they can reproduce. Depending on the severity of an already existing infestation, you may continue to see new fleas jumping on your pet for three months or more (depending on environmental conditions). To prevent new infestations, continue to give NexGard PLUS chews MONTHLY throughout the year. Adult fleas – the ones that you see on an infested pet – make up only ~5% of the total flea population. The developing stages (flea eggs, larvae, and pupae) make up the other ~95%. These developing stages can be found anywhere an infested animal spends time. Commonly infested animals, which spread flea eggs throughout their surroundings, include untreated pets, feral cats, opossums, raccoons, coyotes, etc.
4. Is there a weight or age requirement to give my dog NexGard® PLUS chews?
Answer
NexGard® PLUS chews are safe for dogs and puppies as young as 8 weeks, weighing 4 pounds or more.
5. How long does a dose of NexGard® PLUS chewable tablets last & how often should I treat my dog?
Answer
NexGard® PLUS chews provide powerful protection against fleas and ticks for a full month. Each monthly chew works to prevent heartworm disease by killing any heartworm larvae that were acquired in the previous month. It’s important to ensure that your dog receives a monthly NexGard PLUS chew year-round to keep your dog protected against fleas, ticks, and heartworm disease.
6. Can I start treating my dog with NexGard® PLUS chewables at any time during the year?
Answer
Treatment with NexGard® PLUS chews may begin at any time of the year. It is recommended to treat your dog month after month, year-round no matter the season.
7. Do NexGard® PLUS chews need to be used even if I have an “indoor dog"?
Answer
Yes – it’s a common misconception that indoor pets aren’t exposed to parasites. Fleas are opportunists. Even if your dog only goes outside to do their business, they’re at risk of infestations from fleas and ticks. Fleas can even “hitchhike" into a home on people, and then jump to infest dogs. An infested pet will spread flea eggs throughout the house, which can survive in your carpet or the crannies of your wood floors and then mature to infest other animals in your home. Heartworms are transmitted by mosquitoes. It only takes one mosquito bite to transmit heartworms to your dog – so dogs can be exposed in a very short amount of time. And unfortunately, mosquitoes commonly make their way indoors in search of hosts. Even indoors, pets aren’t safe from the threat.
8. Are NexGard® PLUS chews safe?
Answer
NexGard® PLUS chewable tablets are both effective and safe. NexGard PLUS chews have been evaluated extensively in both laboratory clinical studies, as well as in a field trial in pet dogs. NexGard PLUS chews are safe for use in all breeds of dogs. And it’s approved and safe for use in dogs and puppies 8 weeks of age and older, weighing 4 lbs. or more. The most frequently reported adverse reactions reported in clinical trials were diarrhea, vomiting, lethargy, and itching. NexGard PLUS chews contains afoxolaner, a member of the isoxazoline class, which has been associated with neurologic adverse reactions including tremors, ataxia, and seizures in dogs with or without a history of seizures. Use with caution in dogs with a history of seizures or neurological disorders.
9. Can NexGard® PLUS chews be cut in half?
Answer
NexGard® PLUS chews should not be cut in half, as each NexGard PLUS chewable is designed to provide the correct dose for a dog within a specific weight range. The soft chewables are not designed to be cut in half or split.
10. How do I give NexGard® PLUS chewable tablets to my dog, and what do I do if they spit it up?
Answer
NexGard® PLUS chews can be administered with or without food. Care should be taken to ensure that the dog consumes the complete dose, and that part of the dose is not lost or refused. If a dose is missed, administer a NexGard PLUS chew and resume a monthly dosing schedule. If your dog does not consume the entire dose, please consult your veterinarian.
11. What sizes and options are NexGard® PLUS chews available for purchase?
Answer
NexGard® PLUS chews are available in packs containing either one, three or six beef-flavored chewables and comes in 5 different sizes for (Extra Small 4-8 pounds), (Small 8.1-17 pounds) (Medium 17.1-33 pounds), (Large 33.1-66 pounds) and (Extra Large 66.1-132 pounds) dogs
12. Can NexGard® PLUS chews be used for cats or other animals?
Answer
No, NexGard® PLUS chews should only be used for dogs. Do not give NexGard PLUS chews to cats or other animals.
13. Can NexGard® PLUS chews be used in breeding, pregnant or lactating dogs?
Answer
The safe use of NexGard® PLUS chews in breeding, pregnant or lactating dogs has not been evaluated.
14. Are NexGard® PLUS chews safe for puppies?
Answer
NexGard® PLUS chews are safe for puppies 8 weeks and older that weigh over 4 pounds.
15. Can NexGard® PLUS chews be used with other medications?
Answer
In a well-controlled field study, NexGard® PLUS chews were used concurrently with other medications such as vaccines, antibiotics, non-steroidal anti-inflammatory drugs (NSAIDs), anesthetics, sedatives, analgesics, steroids, anthelmintics, antiemetics, and antipruritics. No adverse reactions were associated with the concurrent use of NexGard PLUS and other medications.
16. How do dogs get Hookworms and Roundworms?
Answer
Roundworms are extremely common in young dogs, infecting over 90% of puppies2. It’s very common for mothers to pass roundworms to their puppies prior to birth or even while the puppies are nursing. Both puppies and adult dogs may also contract roundworms by ingesting roundworm eggs from their environment, while grooming, or by eating infected animals. Hookworm larvae can be transmitted through the skin or by ingesting larvae in contaminated soil or grass in your dog’s environment. Dogs may also contract hookworms by eating other infected animals—usually rodents. Puppies can also be infected if they ingest hookworm larvae while nursing.
17. What is heartworm disease?
Answer
Heartworm disease is an invisible, but potentially fatal threat that occurs in dogs and other animals. Heartworms (Dirofilaria immitis) are parasitic worms that are transmitted to dogs by infected mosquitoes. Microscopic larvae of heartworms develop and grow under the skin, then migrate to the blood vessels of the heart and lungs of the infected animal where they rapidly grow, becoming adults that are 5-12 inches in length.
18. How do dogs get heartworms?
Answer
Dogs get heartworms by being bitten by an infected mosquito. Larvae are deposited on the skin when the infected mosquito bites, then when the infected mosquito leaves, the heartworm larvae enter through the bite wound. One bite is all it takes.
19. What are the signs of Heartworm disease?
Answer
Not all dogs develop noticeable symptoms. While blood tests performed by your veterinarian are the best way to confirm a diagnosis of heartworm disease in dogs, here are five warning signs that are reported in dogs with advanced heartworm disease: 1. A persistent, dry cough is a common sign seen in dogs with heartworm disease. 2. Lethargy and reluctance to exercise are also common signs described in dogs with heartworm disease. 3. Some dogs have a decreased appetite and, as a result, lose weight. 4. As heartworm disease progresses, it can lead to heart failure. You may notice that your dog's belly appears swollen from fluid in the abdomen. 5. In the most advanced cases, dogs can develop more severe respiratory issues like rapid breathing in addition to coughing.
20. How can I reduce the risk of heartworm disease in my dog?
Answer
There are 3 things you can do to help reduce the risk of heartworm disease. 1. Reduce mosquito exposure by eliminating standing water where mosquitoes can breed, avoid known mosquito habitats, and limit outdoor exposure during peak mosquito feeding times.4 2. Use heartworm disease preventives, like monthly NexGard® PLUS chewables, on a year-round basis to safely and effectively prevent heartworm disease by affecting the heartworm larvae before they can grow into dangerous adult heartworms. 3. Get Your Dog Tested Every Year. Before getting a prescription for a heartworm disease preventive, your dog should be tested for heartworms. Talk to your vet about testing options.
21. Can heartworm disease be treated?
Answer
Yes, it can be treated, but heartworm disease is a serious condition that can cause heart failure, permanent damage to your pet's lungs, and even death. Treating heartworm disease is costly and complicated.
22. What is the best number to call regarding any specific product questions for Nexgard PLUS?
Answer
For any specific product questions about Nexgard PLUS, please call Boehringer Ingelheim Animal Health at 1-888-637-4251.

What are NexGard® PLUS CHEWS for Dogs?

NexGard® PLUS CHEWS for Dogs are the ones you want for one-and-done monthly parasite protection for your dog. It gives you the power to protect your dog from fleas and ticks, PLUS heartworm disease, roundworms, and hookworms-all in a delicious, beef-flavored, soft chew. NexGard® PLUS CHEWS for Dogs are safe and approved for puppies as young as 8 weeks old. From the maker of #1 veterinarian-recommended HEARTGARD® Plus Chews (ivermectin/pyrantel), easy-to-give NexGard® PLUS CHEWS for Dogs, provide convenient, monthly parasite protection for the dog you love. Use with caution in dogs with a history of seizures or neurological disorders. Dogs need parasite protection year-round. NexGard® PLUS CHEWS are designed for monthly dosing that’s a delight for your dog – and never a chore – month after month. Fleas pose an ever-present risk for dogs in many parts of the country. While the risk of flea infestations may be higher during warmer months, they can occur at any point throughout the year. NexGard® PLUS CHEWS kill adult fleas fast, before they can lay eggs, for a full month. NexGard® PLUS CHEWS are also approved to kill four species of ticks-the ticks most commonly found on dogs in the US. Heartworm disease is a serious condition that can cause permanent damage even before it can be diagnosed – and just one bite from an infected mosquito could put your pet at risk for this potentially deadly disease. Cases of heartworm disease have been reported in all 50 states -in both indoor and outdoor pets. The American Heartworm Society recommends that all pets receive heartworm disease preventives year-round. Ask your veterinarian about preventing heartworm disease in your dogs with monthly NexGard® PLUS CHEWS. All dogs should be tested for heartworms prior to starting a heartworm disease preventive. With NexGard® PLUS CHEWS , you’re protecting your dog from fleas and ticks, PLUS heartworm disease, 3 species of hookworms, and 2 species of roundworms–all with the tasty beef-flavored chew that’s designed for monthly dosing that’s a delight for your dogs.

Suitable for:

Dogs and Puppies (8 weeks of age and older)

Benefits:

  • Convenient one-and-done monthly dosing for parasite protection
  • Kills adult fleas before they can lay eggs
  • Kills 4 species of ticks (black-legged ticks, brown dog ticks, American dog ticks, & lone star ticks)
  • Effectively prevents heartworm disease
  • Treats and controls 3 species of hookworms and 2 species of roundworms
  • Tasty, soft beef-flavored chew that’s a delight for your dog
  • Safe for puppies as young as 8 weeks of age

How do NexGard® PLUS CHEWS for Dogs work?

NexGard® PLUS CHEWS are designed to prevent heartworm disease caused by Dirofilaria immitis and also to treat and control adult hookworm (Ancylostoma caninum, Ancylostoma braziliense, and Uncinaria stenocephala) and roundworm (Toxocara canis and Toxascaris leonina) infections in dogs and puppies aged 8 weeks and older. Additionally, these chews effectively eliminate adult fleas and are indicated for the treatment and prevention of flea infestations (Ctenocephalides felis), as well as the treatment and control of ticks such as Ixodes scapularis (black-legged tick), Rhipicephalus sanguineus (brown dog tick), Dermacentor variabilis (American dog tick), and Amblyomma americanum (lone star tick) infestations for one month. NexGard® PLUS chews act rapidly to kill fleas before they can lay eggs. In laboratory studies, afoxolaner, one of the active ingredients, started killing fleas just 4 hours after initial administration and demonstrated over 99% effectiveness at 8 hours. These chews provide robust protection against fleas and ticks for the entire month.

Caution:

Not for use in humans. Keep this and all drugs out of the reach of children. In case of accidental ingestion, contact a physician for treatment advice. Keep NexGard® PLUS CHEWS in a secure location out of the reach of dogs, cats, and other animals to prevent accidental ingestion or overdose. The most frequently reported adverse reactions reported in clinical trials were diarrhea, vomiting, lethargy, and itching. NexGard® PLUS (afoxolaner, moxidectin, and pyrantel chewable tablets) contains afoxolaner, a member of the isoxazoline class, which has been associated with neurologic adverse reactions including tremors, ataxia, and seizures in dogs with or without a history of seizures. Use with caution in dogs with a history of seizures or neurological disorders. The safe use of NexGard® PLUS CHEWS has not been evaluated in breeding, pregnant, or lactating dogs. Dogs should be tested for existing heartworm infection prior to starting a heartworm disease preventive. Treatment with fewer than six monthly doses after the last exposure to mosquitoes has not been evaluated and may not provide complete heartworm prevention. Prior to administration of NexGard® PLUS CHEWS, dogs should be tested for existing heartworm infection. At the discretion of the veterinarian, infected dogs should be treated with an adulticide to remove adult heartworms. NexGard® PLUS chews are not effective against adult D. immitis.

How should I store this product?

Store in original package at or below 30°C (86°F) with excursions permitted up to 40°C (104°F).

What is the most important information I should know about NexGard® PLUS CHEWS for Dogs?

NexGard® PLUS CHEWS for Dogs are used to protect your dog from fleas and ticks, PLUS heartworm disease, roundworms, and hookworms. NexGard® PLUS CHEWS are available in four sizes of delicious, beef-flavored soft chew that makes monthly dosing a delight for your dogs. NexGard® PLUS chewable tablets are both effective and safe. NexGard PLUS CHEWS have been evaluated extensively in both laboratory clinical studies, as well as in a field trial in pet dogs. NexGard PLUS CHEWS are safe for use in all breeds of dogs. And it’s approved and safe for use in dogs and puppies 8 weeks of age and older. Afoxolaner, one of the ingredients in NexGard® PLUS CHEWS , is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders.

What should I discuss with my veterinarian before giving NexGard® PLUS CHEWS for Dogs) to my pet?

Provide your veterinarian with a comprehensive health history of your dog, including any past medical conditions, ongoing medications, known allergies, or previous adverse reactions to medications. This information will help the veterinarian assess if NexGard® PLUS is suitable for your pet. Tell your veterinarian if your dog is pregnant, lactating or has a history of seizures. The safe use of NexGard® PLUS (afoxolaner, moxidectin and pyrantel chewable tablets) in breeding, pregnant or lactating dogs has not been evaluated. Afoxolaner, one of the ingredients in NexGard® PLUS chews, is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders. Prior to administration of NexGard PLUS chews, dogs should be tested for existing heartworm infection. At the discretion of the veterinarian, infected dogs should be treated with an adulticide to remove adult heartworms.

How should NexGard®PLUS CHEWS for Dogs be given/administered?

NexGard® PLUS CHEWS require a prescription from your Veterinarian. Remove only one chewable at a time from the foil-backed blister card and administer the appropriate dosage based on your dog's weight. NexGard® PLUS can be administered with or without food. Care should be taken to ensure that the dog consumes the complete dose, and that part of the dose is not lost or refused. NexGard® PLUS should be administered monthly. The first dose must be given within 30 days of the dog's first mosquito exposure, and the final dose within 30 days of the last exposure. When switching from another heartworm preventive, the first NexGard® PLUS dose should be given within 30 days of the last dose of the previous medication. For optimal performance, give the chewable once a month on or about the same day. If there's a delay in treatment, immediate administration and resuming the monthly dosing regimen minimize adult heartworm development. Monthly use of NexGard® PLUS also controls roundworms and hookworms. Measures should be taken to prevent reinfection with intestinal parasites.

What are the potential side effects of NexGard® PLUS CHEWS for Dogs?

The most frequently reported adverse reactions reported in clinical trials were diarrhea, vomiting, lethargy, and itching. NexGard® PLUS (afoxolaner, moxidectin, and pyrantel chewable tablets) contains afoxolaner, a member of the isoxazoline class, which has been associated with neurologic adverse reactions including tremors, ataxia, and seizures in dogs with or without a history of seizures. Use with caution in dogs with a history of seizures or neurological disorders. The safe use of NexGard PLUS chews has not been evaluated in breeding, pregnant, or lactating dogs

What happens if I miss giving a dose of NexGard® PLUS CHEWS for Dogs?

If a dose is missed, administer NexGard® PLUS CHEWS as soon as possible and resume a regular monthly dosing schedule. Missing doses can increase the risk of heartworm infection and flea/tick infestations.

What happens if I overdose my pet on NexGard® PLUS CHEWS for Dogs?

If you accidentally administer more than the recommended dose of NexGard® PLUS to your pet, you should seek immediate veterinary attention. Overdosing can result in symptoms such as increased side effects, gastrointestinal issues (vomiting, diarrhea), tremors, ataxia (lack of coordination), and other neurologic abnormalities. Severe cases of overdose may even lead to seizures or other life-threatening conditions. If you suspect that your pet has been overdosed on NexGard® PLUS or any other medication, do not hesitate to contact your veterinarian or an emergency veterinary clinic immediately for guidance and treatment

What should I avoid while giving NexGard® PLUS CHEWS to my pet?

Avoid giving NexGard® PLUS CHEWS if your pet is pregnant, lactating or has a known history of seizures.

What other drugs will affect NexGard® PLUS CHEWS for Dogs?

There are no known contraindications for the use of NexGard® PLUS CHEWS for Dogs. In a well-controlled field study, NexGard® PLUS CHEWS were used concurrently with other medications such as vaccines, antibiotics, non-steroidal anti-inflammatory drugs (NSAIDs), anesthetics, sedatives, analgesics, steroids, anthelmintics, antiemetics, and antipruritics. No adverse reactions were associated with the concurrent use of NexGard® PLUS CHEWS and other medications.

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NexGard® PLUS CHEWS For Dogs Directions:

  • NexGard® PLUS CHEWS are given orally once a month at the minimum dosage of 1.14 mg/lb (2.5 mg/kg) afoxolaner, 5.45 mcg/lb (12 mcg/kg) moxidectin, and 2.27 mg/lb (5.0 mg/kg) pyrantel (as pamoate salt). Follow the recommended dosing schedule provided for prevention of canine heartworm disease and for the treatment and control of roundworms and hookworms.
  • Remove only one chewable at a time from the foil-backed blister card. Return the card with the remaining chewables to its box to protect the product from light.
  • NexGard® PLUS CHEWS can be administered with or without food. Care should be taken to ensure that the dog consumes the complete dose and that part of the dose is not lost or refused. If a dose is missed, administer NexGard® PLUS CHEWS and resume a monthly dosing schedule.
  • Heartworm Prevention: NexGard® PLUS CHEWS should be administered at monthly intervals year-round or, at a minimum, administration should start within one month of the dog’s first seasonal exposure to mosquitoes and should continue at monthly intervals until at least six months after the dog’s last exposure. When replacing another monthly heartworm preventive product, the first dose of NexGard® PLUS should be given within a month of the last dose of the former medication.
  • Flea Treatment and Prevention: NexGard® PLUS CHEWS should be administered year-round at monthly intervals or started at least one month before fleas become active. To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea control product.
  • Tick Treatment and Control: NexGard® PLUS CHEWS should be administered year-round at monthly intervals or started at least one month before ticks become active.
  • Intestinal Nematode Treatment and Control: NexGard® PLUS CHEWS treat and control adult hookworms (Ancylostoma caninum, Ancylostoma braziliense, and Uncinaria stenocephala) and roundworms (Toxocara canis and Toxascaris leonina). For the treatment of adult hookworm and roundworm infections, NexGard® PLUS should be administered as a single dose. Monthly use of NexGard® PLUS will control any subsequent infections. Dogs may be exposed to and can become infected with hookworms and roundworms throughout the year, regardless of season or climate.
Tip:

Chewables may be broken into pieces and fed to dogs that normally swallow treats whole.

NexGard® PLUS CHEWS For Dogs Dosage:

Monthly Dosing Schedule
Weight of Dog Chews Administered
8.1 - 17 lbs 1 chew
17.1 - 33 lbs 1 chew
33.1 - 66 lbs 1 chew
66.1 - 132 lbs 1 chew
Over 132 lbs Administer the appropriate combination of chewables

NexGard® PLUS CHEWS For Dogs Ingredients:

Nexgard® PLUS CHEWS For Dogs
Body Weight (lbs) Afoxolaner Per Chewable (mg) Moxidectin Per Chewable (mcg) Pyrantel Per Chewable (mg)
8.1 - 17 18.75 90 37.5
17.1 - 33 37.5 180 75
33.1 - 66 75 360 150
66.1 - 132 150 720 300
Ingredients: Afoxolaner, Moxidectin, Pyrantel
Product Details
plus minus

What are NexGard® PLUS CHEWS for Dogs?

NexGard® PLUS CHEWS for Dogs are the ones you want for one-and-done monthly parasite protection for your dog. It gives you the power to protect your dog from fleas and ticks, PLUS heartworm disease, roundworms, and hookworms-all in a delicious, beef-flavored, soft chew. NexGard® PLUS CHEWS for Dogs are safe and approved for puppies as young as 8 weeks old. From the maker of #1 veterinarian-recommended HEARTGARD® Plus Chews (ivermectin/pyrantel), easy-to-give NexGard® PLUS CHEWS for Dogs, provide convenient, monthly parasite protection for the dog you love. Use with caution in dogs with a history of seizures or neurological disorders. Dogs need parasite protection year-round. NexGard® PLUS CHEWS are designed for monthly dosing that’s a delight for your dog – and never a chore – month after month. Fleas pose an ever-present risk for dogs in many parts of the country. While the risk of flea infestations may be higher during warmer months, they can occur at any point throughout the year. NexGard® PLUS CHEWS kill adult fleas fast, before they can lay eggs, for a full month. NexGard® PLUS CHEWS are also approved to kill four species of ticks-the ticks most commonly found on dogs in the US. Heartworm disease is a serious condition that can cause permanent damage even before it can be diagnosed – and just one bite from an infected mosquito could put your pet at risk for this potentially deadly disease. Cases of heartworm disease have been reported in all 50 states -in both indoor and outdoor pets. The American Heartworm Society recommends that all pets receive heartworm disease preventives year-round. Ask your veterinarian about preventing heartworm disease in your dogs with monthly NexGard® PLUS CHEWS. All dogs should be tested for heartworms prior to starting a heartworm disease preventive. With NexGard® PLUS CHEWS , you’re protecting your dog from fleas and ticks, PLUS heartworm disease, 3 species of hookworms, and 2 species of roundworms–all with the tasty beef-flavored chew that’s designed for monthly dosing that’s a delight for your dogs.

Suitable for:

Dogs and Puppies (8 weeks of age and older)

Benefits:

  • Convenient one-and-done monthly dosing for parasite protection
  • Kills adult fleas before they can lay eggs
  • Kills 4 species of ticks (black-legged ticks, brown dog ticks, American dog ticks, & lone star ticks)
  • Effectively prevents heartworm disease
  • Treats and controls 3 species of hookworms and 2 species of roundworms
  • Tasty, soft beef-flavored chew that’s a delight for your dog
  • Safe for puppies as young as 8 weeks of age

How do NexGard® PLUS CHEWS for Dogs work?

NexGard® PLUS CHEWS are designed to prevent heartworm disease caused by Dirofilaria immitis and also to treat and control adult hookworm (Ancylostoma caninum, Ancylostoma braziliense, and Uncinaria stenocephala) and roundworm (Toxocara canis and Toxascaris leonina) infections in dogs and puppies aged 8 weeks and older. Additionally, these chews effectively eliminate adult fleas and are indicated for the treatment and prevention of flea infestations (Ctenocephalides felis), as well as the treatment and control of ticks such as Ixodes scapularis (black-legged tick), Rhipicephalus sanguineus (brown dog tick), Dermacentor variabilis (American dog tick), and Amblyomma americanum (lone star tick) infestations for one month. NexGard® PLUS chews act rapidly to kill fleas before they can lay eggs. In laboratory studies, afoxolaner, one of the active ingredients, started killing fleas just 4 hours after initial administration and demonstrated over 99% effectiveness at 8 hours. These chews provide robust protection against fleas and ticks for the entire month.

Caution:

Not for use in humans. Keep this and all drugs out of the reach of children. In case of accidental ingestion, contact a physician for treatment advice. Keep NexGard® PLUS CHEWS in a secure location out of the reach of dogs, cats, and other animals to prevent accidental ingestion or overdose. The most frequently reported adverse reactions reported in clinical trials were diarrhea, vomiting, lethargy, and itching. NexGard® PLUS (afoxolaner, moxidectin, and pyrantel chewable tablets) contains afoxolaner, a member of the isoxazoline class, which has been associated with neurologic adverse reactions including tremors, ataxia, and seizures in dogs with or without a history of seizures. Use with caution in dogs with a history of seizures or neurological disorders. The safe use of NexGard® PLUS CHEWS has not been evaluated in breeding, pregnant, or lactating dogs. Dogs should be tested for existing heartworm infection prior to starting a heartworm disease preventive. Treatment with fewer than six monthly doses after the last exposure to mosquitoes has not been evaluated and may not provide complete heartworm prevention. Prior to administration of NexGard® PLUS CHEWS, dogs should be tested for existing heartworm infection. At the discretion of the veterinarian, infected dogs should be treated with an adulticide to remove adult heartworms. NexGard® PLUS chews are not effective against adult D. immitis.

How should I store this product?

Store in original package at or below 30°C (86°F) with excursions permitted up to 40°C (104°F).

What is the most important information I should know about NexGard® PLUS CHEWS for Dogs?

NexGard® PLUS CHEWS for Dogs are used to protect your dog from fleas and ticks, PLUS heartworm disease, roundworms, and hookworms. NexGard® PLUS CHEWS are available in four sizes of delicious, beef-flavored soft chew that makes monthly dosing a delight for your dogs. NexGard® PLUS chewable tablets are both effective and safe. NexGard PLUS CHEWS have been evaluated extensively in both laboratory clinical studies, as well as in a field trial in pet dogs. NexGard PLUS CHEWS are safe for use in all breeds of dogs. And it’s approved and safe for use in dogs and puppies 8 weeks of age and older. Afoxolaner, one of the ingredients in NexGard® PLUS CHEWS , is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders.

What should I discuss with my veterinarian before giving NexGard® PLUS CHEWS for Dogs) to my pet?

Provide your veterinarian with a comprehensive health history of your dog, including any past medical conditions, ongoing medications, known allergies, or previous adverse reactions to medications. This information will help the veterinarian assess if NexGard® PLUS is suitable for your pet. Tell your veterinarian if your dog is pregnant, lactating or has a history of seizures. The safe use of NexGard® PLUS (afoxolaner, moxidectin and pyrantel chewable tablets) in breeding, pregnant or lactating dogs has not been evaluated. Afoxolaner, one of the ingredients in NexGard® PLUS chews, is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders. Prior to administration of NexGard PLUS chews, dogs should be tested for existing heartworm infection. At the discretion of the veterinarian, infected dogs should be treated with an adulticide to remove adult heartworms.

How should NexGard®PLUS CHEWS for Dogs be given/administered?

NexGard® PLUS CHEWS require a prescription from your Veterinarian. Remove only one chewable at a time from the foil-backed blister card and administer the appropriate dosage based on your dog's weight. NexGard® PLUS can be administered with or without food. Care should be taken to ensure that the dog consumes the complete dose, and that part of the dose is not lost or refused. NexGard® PLUS should be administered monthly. The first dose must be given within 30 days of the dog's first mosquito exposure, and the final dose within 30 days of the last exposure. When switching from another heartworm preventive, the first NexGard® PLUS dose should be given within 30 days of the last dose of the previous medication. For optimal performance, give the chewable once a month on or about the same day. If there's a delay in treatment, immediate administration and resuming the monthly dosing regimen minimize adult heartworm development. Monthly use of NexGard® PLUS also controls roundworms and hookworms. Measures should be taken to prevent reinfection with intestinal parasites.

What are the potential side effects of NexGard® PLUS CHEWS for Dogs?

The most frequently reported adverse reactions reported in clinical trials were diarrhea, vomiting, lethargy, and itching. NexGard® PLUS (afoxolaner, moxidectin, and pyrantel chewable tablets) contains afoxolaner, a member of the isoxazoline class, which has been associated with neurologic adverse reactions including tremors, ataxia, and seizures in dogs with or without a history of seizures. Use with caution in dogs with a history of seizures or neurological disorders. The safe use of NexGard PLUS chews has not been evaluated in breeding, pregnant, or lactating dogs

What happens if I miss giving a dose of NexGard® PLUS CHEWS for Dogs?

If a dose is missed, administer NexGard® PLUS CHEWS as soon as possible and resume a regular monthly dosing schedule. Missing doses can increase the risk of heartworm infection and flea/tick infestations.

What happens if I overdose my pet on NexGard® PLUS CHEWS for Dogs?

If you accidentally administer more than the recommended dose of NexGard® PLUS to your pet, you should seek immediate veterinary attention. Overdosing can result in symptoms such as increased side effects, gastrointestinal issues (vomiting, diarrhea), tremors, ataxia (lack of coordination), and other neurologic abnormalities. Severe cases of overdose may even lead to seizures or other life-threatening conditions. If you suspect that your pet has been overdosed on NexGard® PLUS or any other medication, do not hesitate to contact your veterinarian or an emergency veterinary clinic immediately for guidance and treatment

What should I avoid while giving NexGard® PLUS CHEWS to my pet?

Avoid giving NexGard® PLUS CHEWS if your pet is pregnant, lactating or has a known history of seizures.

What other drugs will affect NexGard® PLUS CHEWS for Dogs?

There are no known contraindications for the use of NexGard® PLUS CHEWS for Dogs. In a well-controlled field study, NexGard® PLUS CHEWS were used concurrently with other medications such as vaccines, antibiotics, non-steroidal anti-inflammatory drugs (NSAIDs), anesthetics, sedatives, analgesics, steroids, anthelmintics, antiemetics, and antipruritics. No adverse reactions were associated with the concurrent use of NexGard® PLUS CHEWS and other medications.

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How to use
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NexGard® PLUS CHEWS For Dogs Directions:

  • NexGard® PLUS CHEWS are given orally once a month at the minimum dosage of 1.14 mg/lb (2.5 mg/kg) afoxolaner, 5.45 mcg/lb (12 mcg/kg) moxidectin, and 2.27 mg/lb (5.0 mg/kg) pyrantel (as pamoate salt). Follow the recommended dosing schedule provided for prevention of canine heartworm disease and for the treatment and control of roundworms and hookworms.
  • Remove only one chewable at a time from the foil-backed blister card. Return the card with the remaining chewables to its box to protect the product from light.
  • NexGard® PLUS CHEWS can be administered with or without food. Care should be taken to ensure that the dog consumes the complete dose and that part of the dose is not lost or refused. If a dose is missed, administer NexGard® PLUS CHEWS and resume a monthly dosing schedule.
  • Heartworm Prevention: NexGard® PLUS CHEWS should be administered at monthly intervals year-round or, at a minimum, administration should start within one month of the dog’s first seasonal exposure to mosquitoes and should continue at monthly intervals until at least six months after the dog’s last exposure. When replacing another monthly heartworm preventive product, the first dose of NexGard® PLUS should be given within a month of the last dose of the former medication.
  • Flea Treatment and Prevention: NexGard® PLUS CHEWS should be administered year-round at monthly intervals or started at least one month before fleas become active. To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea control product.
  • Tick Treatment and Control: NexGard® PLUS CHEWS should be administered year-round at monthly intervals or started at least one month before ticks become active.
  • Intestinal Nematode Treatment and Control: NexGard® PLUS CHEWS treat and control adult hookworms (Ancylostoma caninum, Ancylostoma braziliense, and Uncinaria stenocephala) and roundworms (Toxocara canis and Toxascaris leonina). For the treatment of adult hookworm and roundworm infections, NexGard® PLUS should be administered as a single dose. Monthly use of NexGard® PLUS will control any subsequent infections. Dogs may be exposed to and can become infected with hookworms and roundworms throughout the year, regardless of season or climate.
Tip:

Chewables may be broken into pieces and fed to dogs that normally swallow treats whole.

NexGard® PLUS CHEWS For Dogs Dosage:

Monthly Dosing Schedule
Weight of Dog Chews Administered
8.1 - 17 lbs 1 chew
17.1 - 33 lbs 1 chew
33.1 - 66 lbs 1 chew
66.1 - 132 lbs 1 chew
Over 132 lbs Administer the appropriate combination of chewables
Ingredients
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NexGard® PLUS CHEWS For Dogs Ingredients:

Nexgard® PLUS CHEWS For Dogs
Body Weight (lbs) Afoxolaner Per Chewable (mg) Moxidectin Per Chewable (mcg) Pyrantel Per Chewable (mg)
8.1 - 17 18.75 90 37.5
17.1 - 33 37.5 180 75
33.1 - 66 75 360 150
66.1 - 132 150 720 300
Ingredients: Afoxolaner, Moxidectin, Pyrantel
Q&A
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1. How do I use NexGard® PLUS (afoxaloner, moxidectin, pyrantel chewable tablets) for Dogs?
Answer
NexGard® PLUS (afoxaloner, moxidectin, pyrantel chewable tablets) is used to protect your dog from fleas and ticks, PLUS heartworm disease, roundworms, and hookworms. NexGard PLUS chews are available in a delicious, beef-flavored soft chew that makes monthly dosing a delight for your dogs. For each monthly dose, a chew can be given with or without food. See the product label for full dosing instructions, and always check with your vet regarding their recommendations for your pet.
2. How fast do NexGard® PLUS chews work?
Answer
NexGard® PLUS chews kill fleas fast before they can lay eggs. In a well-controlled laboratory study, afoxolaner alone began to kill fleas 4 hours after initial administration and was >99% effective at 8 hours. NexGard PLUS chews provide powerful protection against fleas and ticks for a full month. NexGard PLUS chews work to prevent heartworm disease by killing any heartworm larvae that were acquired in the previous month. That’s why it is so important for your dog to receive the appropriate dose of NexGard PLUS chews every month, year-round. The pyrantel in NexGard PLUS chews is a dewormer that treats and controls 3 species of hookworms and 2 species of roundworms.
3. Why am I still seeing fleas on my dog after using NexGard® PLUS chewable tablets?
Answer
You are likely seeing NEW fleas on your pet, which are jumping on your dog as it moves through infested areas. These fleas will be killed quickly by NexGard® PLUS chews before they can reproduce. Depending on the severity of an already existing infestation, you may continue to see new fleas jumping on your pet for three months or more (depending on environmental conditions). To prevent new infestations, continue to give NexGard PLUS chews MONTHLY throughout the year. Adult fleas – the ones that you see on an infested pet – make up only ~5% of the total flea population. The developing stages (flea eggs, larvae, and pupae) make up the other ~95%. These developing stages can be found anywhere an infested animal spends time. Commonly infested animals, which spread flea eggs throughout their surroundings, include untreated pets, feral cats, opossums, raccoons, coyotes, etc.
4. Is there a weight or age requirement to give my dog NexGard® PLUS chews?
Answer
NexGard® PLUS chews are safe for dogs and puppies as young as 8 weeks, weighing 4 pounds or more.
5. How long does a dose of NexGard® PLUS chewable tablets last & how often should I treat my dog?
Answer
NexGard® PLUS chews provide powerful protection against fleas and ticks for a full month. Each monthly chew works to prevent heartworm disease by killing any heartworm larvae that were acquired in the previous month. It’s important to ensure that your dog receives a monthly NexGard PLUS chew year-round to keep your dog protected against fleas, ticks, and heartworm disease.
6. Can I start treating my dog with NexGard® PLUS chewables at any time during the year?
Answer
Treatment with NexGard® PLUS chews may begin at any time of the year. It is recommended to treat your dog month after month, year-round no matter the season.
7. Do NexGard® PLUS chews need to be used even if I have an “indoor dog"?
Answer
Yes – it’s a common misconception that indoor pets aren’t exposed to parasites. Fleas are opportunists. Even if your dog only goes outside to do their business, they’re at risk of infestations from fleas and ticks. Fleas can even “hitchhike" into a home on people, and then jump to infest dogs. An infested pet will spread flea eggs throughout the house, which can survive in your carpet or the crannies of your wood floors and then mature to infest other animals in your home. Heartworms are transmitted by mosquitoes. It only takes one mosquito bite to transmit heartworms to your dog – so dogs can be exposed in a very short amount of time. And unfortunately, mosquitoes commonly make their way indoors in search of hosts. Even indoors, pets aren’t safe from the threat.
8. Are NexGard® PLUS chews safe?
Answer
NexGard® PLUS chewable tablets are both effective and safe. NexGard PLUS chews have been evaluated extensively in both laboratory clinical studies, as well as in a field trial in pet dogs. NexGard PLUS chews are safe for use in all breeds of dogs. And it’s approved and safe for use in dogs and puppies 8 weeks of age and older, weighing 4 lbs. or more. The most frequently reported adverse reactions reported in clinical trials were diarrhea, vomiting, lethargy, and itching. NexGard PLUS chews contains afoxolaner, a member of the isoxazoline class, which has been associated with neurologic adverse reactions including tremors, ataxia, and seizures in dogs with or without a history of seizures. Use with caution in dogs with a history of seizures or neurological disorders.
9. Can NexGard® PLUS chews be cut in half?
Answer
NexGard® PLUS chews should not be cut in half, as each NexGard PLUS chewable is designed to provide the correct dose for a dog within a specific weight range. The soft chewables are not designed to be cut in half or split.
10. How do I give NexGard® PLUS chewable tablets to my dog, and what do I do if they spit it up?
Answer
NexGard® PLUS chews can be administered with or without food. Care should be taken to ensure that the dog consumes the complete dose, and that part of the dose is not lost or refused. If a dose is missed, administer a NexGard PLUS chew and resume a monthly dosing schedule. If your dog does not consume the entire dose, please consult your veterinarian.
11. What sizes and options are NexGard® PLUS chews available for purchase?
Answer
NexGard® PLUS chews are available in packs containing either one, three or six beef-flavored chewables and comes in 5 different sizes for (Extra Small 4-8 pounds), (Small 8.1-17 pounds) (Medium 17.1-33 pounds), (Large 33.1-66 pounds) and (Extra Large 66.1-132 pounds) dogs
12. Can NexGard® PLUS chews be used for cats or other animals?
Answer
No, NexGard® PLUS chews should only be used for dogs. Do not give NexGard PLUS chews to cats or other animals.
13. Can NexGard® PLUS chews be used in breeding, pregnant or lactating dogs?
Answer
The safe use of NexGard® PLUS chews in breeding, pregnant or lactating dogs has not been evaluated.
14. Are NexGard® PLUS chews safe for puppies?
Answer
NexGard® PLUS chews are safe for puppies 8 weeks and older that weigh over 4 pounds.
15. Can NexGard® PLUS chews be used with other medications?
Answer
In a well-controlled field study, NexGard® PLUS chews were used concurrently with other medications such as vaccines, antibiotics, non-steroidal anti-inflammatory drugs (NSAIDs), anesthetics, sedatives, analgesics, steroids, anthelmintics, antiemetics, and antipruritics. No adverse reactions were associated with the concurrent use of NexGard PLUS and other medications.
16. How do dogs get Hookworms and Roundworms?
Answer
Roundworms are extremely common in young dogs, infecting over 90% of puppies2. It’s very common for mothers to pass roundworms to their puppies prior to birth or even while the puppies are nursing. Both puppies and adult dogs may also contract roundworms by ingesting roundworm eggs from their environment, while grooming, or by eating infected animals. Hookworm larvae can be transmitted through the skin or by ingesting larvae in contaminated soil or grass in your dog’s environment. Dogs may also contract hookworms by eating other infected animals—usually rodents. Puppies can also be infected if they ingest hookworm larvae while nursing.
17. What is heartworm disease?
Answer
Heartworm disease is an invisible, but potentially fatal threat that occurs in dogs and other animals. Heartworms (Dirofilaria immitis) are parasitic worms that are transmitted to dogs by infected mosquitoes. Microscopic larvae of heartworms develop and grow under the skin, then migrate to the blood vessels of the heart and lungs of the infected animal where they rapidly grow, becoming adults that are 5-12 inches in length.
18. How do dogs get heartworms?
Answer
Dogs get heartworms by being bitten by an infected mosquito. Larvae are deposited on the skin when the infected mosquito bites, then when the infected mosquito leaves, the heartworm larvae enter through the bite wound. One bite is all it takes.
19. What are the signs of Heartworm disease?
Answer
Not all dogs develop noticeable symptoms. While blood tests performed by your veterinarian are the best way to confirm a diagnosis of heartworm disease in dogs, here are five warning signs that are reported in dogs with advanced heartworm disease: 1. A persistent, dry cough is a common sign seen in dogs with heartworm disease. 2. Lethargy and reluctance to exercise are also common signs described in dogs with heartworm disease. 3. Some dogs have a decreased appetite and, as a result, lose weight. 4. As heartworm disease progresses, it can lead to heart failure. You may notice that your dog's belly appears swollen from fluid in the abdomen. 5. In the most advanced cases, dogs can develop more severe respiratory issues like rapid breathing in addition to coughing.
20. How can I reduce the risk of heartworm disease in my dog?
Answer
There are 3 things you can do to help reduce the risk of heartworm disease. 1. Reduce mosquito exposure by eliminating standing water where mosquitoes can breed, avoid known mosquito habitats, and limit outdoor exposure during peak mosquito feeding times.4 2. Use heartworm disease preventives, like monthly NexGard® PLUS chewables, on a year-round basis to safely and effectively prevent heartworm disease by affecting the heartworm larvae before they can grow into dangerous adult heartworms. 3. Get Your Dog Tested Every Year. Before getting a prescription for a heartworm disease preventive, your dog should be tested for heartworms. Talk to your vet about testing options.
21. Can heartworm disease be treated?
Answer
Yes, it can be treated, but heartworm disease is a serious condition that can cause heart failure, permanent damage to your pet's lungs, and even death. Treating heartworm disease is costly and complicated.
22. What is the best number to call regarding any specific product questions for Nexgard PLUS?
Answer
For any specific product questions about Nexgard PLUS, please call Boehringer Ingelheim Animal Health at 1-888-637-4251.
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