Prescription Item Prescription Required
At a Glance
  • Effective against a wide array of bacterial infections in dogs and cats
  • Simple once-a-day dosing

Sulfamethoxazole and Trimethoprim Tablets

5 out of 5 Customer Rating
0/5 Star symbol Star symbol Star symbol Star symbol Star symbol Write the first review
$0.19
$0.14 with code CARE25 (Save 26%)
Prescription

Prescription required.

Prescription item

Save $0 by joining PetPlus

$0.19
$0.14 with code CARE25 (Save 26%)
Prescription Item

Prescription required.

Prescription item

Save $0 by joining PetPlus

save big
At a Glance
  • Effective against a wide array of bacterial infections in dogs and cats
  • Simple once-a-day dosing
Up to $30 off, exclusions apply
$0.19 -0% future orders
Ship every:
  • Pause, skip or cancel anytime
  • Free access to licensed vets
Quantity:
Please select all product options.
Checkbox Temporarily Out of Stock
Be the first to know when it’s available:
Please select all product options.

null

delivery-truck-speed
Free shipping over $48* | Arrives in 1-3 days on average
About this product
1. Are sulfamethoxazole and trimethoprim safe for dogs?
Answer
Sulfamethoxazole and trimethoprim are commonly used antibiotics in both human and veterinary medicine. These drugs can be used to treat a variety of bacterial infections in dogs, such as urinary tract infections, respiratory tract infections, and skin infections. However, like any medication, sulfamethoxazole and trimethoprim can have potential side effects and may not be safe for all dogs. Some dogs may be allergic to these antibiotics or may have underlying health conditions that make them more susceptible to adverse reactions. Sulfamethoxazole and trimethoprim should not be used in dogs with liver tissue damage, blood cell problems or in dogs that are dehydrated or at an increased risk for urinary stones. Additionally, these antibiotics should not be used in dogs that are known to be allergic to sulfonamides or have had an adverse reaction to these medications in the past.
2. How much sulfamethoxazole and trimethoprim should I give my dog?
Answer
In general, the standard dosage of sulfamethoxazole and trimethoprim for dogs is 30-45 mg/kg of body weight, given orally every 12-24 hours. The duration of treatment will depend on the type and severity of the infection being treated, but it is typically continued for at least 5-7 days. However, the dosage of sulfamethoxazole and trimethoprim that is appropriate for your dog will depend on several factors, including the dog's weight, age, and overall health, as well as the condition being treated.
3. What are the side effects of sulfamethoxazole-trimethoprim in dogs?
Answer
Sulfamethoxazole-trimethoprim is generally a safe and effective antibiotic when used appropriately in dogs. However, like all medications, it can cause side effects in some dogs. Common side effects of sulfamethoxazole-trimethoprim in dogs may include loss of appetite, vomiting, diarrhea, lethargy or weakness, skin rash or hives, itching or other signs of an allergic reaction, blood disorders (such as anemia or low platelet counts), kidney damage or dysfunction, and liver damage or dysfunction. In rare cases, sulfamethoxazole-trimethoprim can cause serious side effects, such as anaphylactic shock or a severe blood disorder called immune-mediated hemolytic anemia. If you notice any signs of a severe reaction, such as difficulty breathing, pale gums, or collapse, seek emergency veterinary care immediately.
4. Is sulfamethoxazole a strong antibiotic?
Answer
Sulfamethoxazole is a broad-spectrum antibiotic that is commonly used to treat bacterial infections in both humans and animals. When used in combination with trimethoprim, it is commonly referred to as "sulfamethoxazole-trimethoprim" or "SMZ-TMP." Sulfamethoxazole is generally considered to be a moderate to strong antibiotic and is effective against many different types of bacteria, including both gram-positive and gram-negative bacteria. However, like all antibiotics, they may not be effective against all types of bacteria, and some strains of bacteria may be resistant to their effects. The strength of an antibiotic depends on several factors, including the specific bacteria being targeted, the dosage and duration of treatment, and the individual patient's response to the medication. In some cases, sulfamethoxazole may be prescribed as a first-line treatment for certain types of bacterial infections, while in other cases, stronger or more targeted antibiotics may be necessary.
5. What kind of antibiotic is sulfamethoxazole for?
Answer
Sulfamethoxazole is a type of antibiotic that belongs to a class of drugs called sulfonamides. It works by inhibiting the growth and reproduction of bacteria, which helps to treat and prevent bacterial infections. Sulfamethoxazole is effective against a wide range of gram-positive and gram-negative bacteria, including some strains that are resistant to other antibiotics. It is commonly used to treat infections of the respiratory tract, urinary tract, skin, and soft tissues, as well as certain types of gastrointestinal infections. Sulfamethoxazole is often used in combination with another antibiotic called trimethoprim, which enhances its antibacterial effects and broadens its spectrum of activity.
6. How long does it take for sulfamethoxazole to work?
Answer
The length of time it takes for sulfamethoxazole to work in dogs can vary depending on the specific condition being treated and the severity of the infection. In general, sulfamethoxazole can start to improve symptoms within a few days of starting treatment, but it's necessary to complete the full course of treatment as prescribed by your veterinarian, even if your dog's symptoms improve. For uncomplicated urinary tract infections, sulfamethoxazole is typically prescribed for a course of 3-5 days. For more severe infections or infections that involve other parts of the body, such as the respiratory tract or skin, treatment may last for 7-14 days or longer.
7. Is sulfamethoxazole the same as amoxicillin?
Answer
No, sulfamethoxazole and amoxicillin are different antibiotics that belong to different classes of drugs and work in different ways to fight bacterial infections. Sulfamethoxazole is a sulfonamide antibiotic that works by inhibiting the growth and reproduction of bacteria, while amoxicillin is a penicillin-type antibiotic that works by blocking the formation of bacterial cell walls. While both sulfamethoxazole and amoxicillin are broad-spectrum antibiotics that can be used to treat a variety of bacterial infections, they are not interchangeable and are typically prescribed based on the specific type of infection being treated and the individual patient's needs. In some cases, a combination of different antibiotics may be prescribed to provide broader coverage against different types of bacteria.

What are Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP)?

Sulfamethoxazole and Trimethoprim (SMZ-TMP) Tablets are a combination antibiotic used to treat respiratory, urinary tract, skin, or gastrointestinal infections, and other conditions. Sulfamethoxazole and Trimethoprim (SMZ-TMP) Tablets require a prescription from your veterinarian, and are sold per tablet.

For:

Cats and Dogs

Benefits:

  • Effective against a wide array of bacterial infections in dogs and cats
  • Simple once-a-day dosing

How do Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP) work?

Sulfamethoxazole is a sulfonamide antibiotic that limits the growth of bacteria. Sulfonamides inhibit synthesis of folic acid, important to bacterial DNA synthesis. Trimethoprim works by starving the bacteria of nucleotides necessary for DNA replication.

Cautions:

Do not use in pregnant or nursing animals. Leave plenty of water for your pet to drink. Report any unusual side effects to your veterinarian.

Brand Name:

Bactrim, Bactrim DS (Roche), Septra, Septra DS (Monarch)

Generic Name:

Sulfamethoxazole (SMZ) and Trimethoprim (TMP) (sulfa-meth-ox'-ah-zole with tri-meth'-o-prim)

What is the most important information I should know about Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP) ?

Sulfamethoxadole and Trimethoprim is a prescription medication that is not FDA-approved for veterinary use; but it is commonly accepted practice for veterinarians to prescribe this medication for dogs and cats. Sulfamethoxazole and Trimethoprim Tablets are available as scored tablets. The usual initial dose for dogs and cats is 13mg/pound every 24 hours, which may be divided into two doses given 12 hours apart. Always follow the dosage instructions provided by your veterinarian. Do not give Sulfamethoxazole and Trimethoprim Tablets to any pet other than the pet for whom it was prescribed. Sulfamethoxazole and Trimethoprim Tablets are not for use in animals allergic to it or other sulfa drugs.

What should I discuss with my veterinarian before giving Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP) to my pet?

Tell your veterinarian if your pet has liver or kidney disease, G6PD (glucose-6-phosphate dehydrogenase) deficiency, or if your pet is pregnant or lactating.

How should Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP) be given?

Give this medication exactly as directed by your veterinarian. The dose and duration of therapy will depend on the type of infection and the response to the medication. Give all of the medication your veterinarian has prescribed. Symptoms may start to improve before the infection is completely treated. Give Sulfamethoxazole and Trimethoprim Tablets by mouth. The tablets may be given with food, and they can be crushed and put in food if needed. Allow plenty of water for your pet to drink. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. Store Sulfamethoxazole and Trimethoprim Tablets at room temperature away from moisture and heat. Keep this medication away from children and pets.

What are the possible side effects of Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP)?

Stop giving the medication and seek emergency veterinary medical attention if your pet experiences an allergic reaction (difficulty breathing, closing of the throat, swelling of the lips, tongue or face, or hives), unusual bleeding or bruising, or yellow skin or eyes. Other less serious side effects may also occur. Continue to give the medication and talk to your veterinarian if your pet experiences fatigue, dizziness, nausea, vomiting, decreased appetite, diarrhea, weakness, or increased sensitivity to the sun. Side effects other than those listed may occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet.

What happens if I miss giving a dose of Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP)?

Give the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the dose missed and give only the next regularly scheduled dose. Do not give a double dose of the medication.

What happens if I overdose my pet on Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP)?

Seek emergency veterinary medical treatment. Symptoms of overdose may include nausea, vomiting, decreased appetite, diarrhea, yellowing of the eyes, decreased urine production, bloody urine, and coma.

What should I avoid while giving Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP) to my pet?

Do not give this medication to pets allergic to it or other sulfonamides (sulfa drugs). Avoid prolonged exposure to sunlight. This medication may increase sensitivity of the skin to sunlight.

What other drugs will affect Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP)?

Before giving this medication to your pet, tell your veterinarian if your pet is being given warfarin, aspirin, glipizide, or phenytoin. Drugs other than those listed may also interact with sulfamethoxazole and trimethoprim. Talk to your veterinarian or pharmacist before giving prescription or over-the-counter medications.

See more

Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP) Directions:

  • Sulfamethoxazole and Trimethoprim Tablets Double Strength are a broad-spectrum prescription antibiotic that is used in dogs and cats to treat respiratory infections such as bronchitis, urinary tract infections, skin infections, ear infections, gastrointestinal infections, and certain types of diarrhea.
  • Sulfamethoxazole and Trimethoprim Tablets Double Strength are not FDA-approved for use in veterinary medicine; however, it is a commonly accepted practice for veterinarians to prescribe this medication for dogs and cats.
  • Give this medication exactly as directed by your veterinarian.
Tip:

The dose and duration of therapy will depend on the type of infection and the response to the Sulfamethoxazole and Trimethoprim Tablets Double Strength.

Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP) Dosage:

Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP) Dosage for Cats
Weight Dosage
All weights Give 13 mg per pound daily divided into two equal doses ever 12 hours. You may crush the tablets and put them in food if needed. Allow plenty of water for your pet to drink.
Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP) Dosage for Dogs
Weight Dosage
All weights Give 13 mg per pound daily divided into two equal doses ever 12 hours. You may crush the tablets and put them in food if needed. Allow plenty of water for your pet to drink.
Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP) Dosage for Horses
Horses
Do not use!

Storage:

Store at room temperature away from moisture and heat.

Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP) Ingredients:

Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP)
Active Ingredients (per tablet) Amount
Sulfamethoxazole 800 mg
Trimethoprim 160 mg
Product Details
plus minus

What are Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP)?

Sulfamethoxazole and Trimethoprim (SMZ-TMP) Tablets are a combination antibiotic used to treat respiratory, urinary tract, skin, or gastrointestinal infections, and other conditions. Sulfamethoxazole and Trimethoprim (SMZ-TMP) Tablets require a prescription from your veterinarian, and are sold per tablet.

For:

Cats and Dogs

Benefits:

  • Effective against a wide array of bacterial infections in dogs and cats
  • Simple once-a-day dosing

How do Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP) work?

Sulfamethoxazole is a sulfonamide antibiotic that limits the growth of bacteria. Sulfonamides inhibit synthesis of folic acid, important to bacterial DNA synthesis. Trimethoprim works by starving the bacteria of nucleotides necessary for DNA replication.

Cautions:

Do not use in pregnant or nursing animals. Leave plenty of water for your pet to drink. Report any unusual side effects to your veterinarian.

Brand Name:

Bactrim, Bactrim DS (Roche), Septra, Septra DS (Monarch)

Generic Name:

Sulfamethoxazole (SMZ) and Trimethoprim (TMP) (sulfa-meth-ox'-ah-zole with tri-meth'-o-prim)

What is the most important information I should know about Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP) ?

Sulfamethoxadole and Trimethoprim is a prescription medication that is not FDA-approved for veterinary use; but it is commonly accepted practice for veterinarians to prescribe this medication for dogs and cats. Sulfamethoxazole and Trimethoprim Tablets are available as scored tablets. The usual initial dose for dogs and cats is 13mg/pound every 24 hours, which may be divided into two doses given 12 hours apart. Always follow the dosage instructions provided by your veterinarian. Do not give Sulfamethoxazole and Trimethoprim Tablets to any pet other than the pet for whom it was prescribed. Sulfamethoxazole and Trimethoprim Tablets are not for use in animals allergic to it or other sulfa drugs.

What should I discuss with my veterinarian before giving Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP) to my pet?

Tell your veterinarian if your pet has liver or kidney disease, G6PD (glucose-6-phosphate dehydrogenase) deficiency, or if your pet is pregnant or lactating.

How should Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP) be given?

Give this medication exactly as directed by your veterinarian. The dose and duration of therapy will depend on the type of infection and the response to the medication. Give all of the medication your veterinarian has prescribed. Symptoms may start to improve before the infection is completely treated. Give Sulfamethoxazole and Trimethoprim Tablets by mouth. The tablets may be given with food, and they can be crushed and put in food if needed. Allow plenty of water for your pet to drink. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. Store Sulfamethoxazole and Trimethoprim Tablets at room temperature away from moisture and heat. Keep this medication away from children and pets.

What are the possible side effects of Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP)?

Stop giving the medication and seek emergency veterinary medical attention if your pet experiences an allergic reaction (difficulty breathing, closing of the throat, swelling of the lips, tongue or face, or hives), unusual bleeding or bruising, or yellow skin or eyes. Other less serious side effects may also occur. Continue to give the medication and talk to your veterinarian if your pet experiences fatigue, dizziness, nausea, vomiting, decreased appetite, diarrhea, weakness, or increased sensitivity to the sun. Side effects other than those listed may occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet.

What happens if I miss giving a dose of Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP)?

Give the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the dose missed and give only the next regularly scheduled dose. Do not give a double dose of the medication.

What happens if I overdose my pet on Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP)?

Seek emergency veterinary medical treatment. Symptoms of overdose may include nausea, vomiting, decreased appetite, diarrhea, yellowing of the eyes, decreased urine production, bloody urine, and coma.

What should I avoid while giving Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP) to my pet?

Do not give this medication to pets allergic to it or other sulfonamides (sulfa drugs). Avoid prolonged exposure to sunlight. This medication may increase sensitivity of the skin to sunlight.

What other drugs will affect Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP)?

Before giving this medication to your pet, tell your veterinarian if your pet is being given warfarin, aspirin, glipizide, or phenytoin. Drugs other than those listed may also interact with sulfamethoxazole and trimethoprim. Talk to your veterinarian or pharmacist before giving prescription or over-the-counter medications.

See more
How to use
plus minus

Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP) Directions:

  • Sulfamethoxazole and Trimethoprim Tablets Double Strength are a broad-spectrum prescription antibiotic that is used in dogs and cats to treat respiratory infections such as bronchitis, urinary tract infections, skin infections, ear infections, gastrointestinal infections, and certain types of diarrhea.
  • Sulfamethoxazole and Trimethoprim Tablets Double Strength are not FDA-approved for use in veterinary medicine; however, it is a commonly accepted practice for veterinarians to prescribe this medication for dogs and cats.
  • Give this medication exactly as directed by your veterinarian.
Tip:

The dose and duration of therapy will depend on the type of infection and the response to the Sulfamethoxazole and Trimethoprim Tablets Double Strength.

Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP) Dosage:

Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP) Dosage for Cats
Weight Dosage
All weights Give 13 mg per pound daily divided into two equal doses ever 12 hours. You may crush the tablets and put them in food if needed. Allow plenty of water for your pet to drink.
Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP) Dosage for Dogs
Weight Dosage
All weights Give 13 mg per pound daily divided into two equal doses ever 12 hours. You may crush the tablets and put them in food if needed. Allow plenty of water for your pet to drink.
Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP) Dosage for Horses
Horses
Do not use!

Storage:

Store at room temperature away from moisture and heat.

Ingredients
plus minus

Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP) Ingredients:

Sulfamethoxazole and Trimethoprim Tablets (SMZ-TMP)
Active Ingredients (per tablet) Amount
Sulfamethoxazole 800 mg
Trimethoprim 160 mg
1. Are sulfamethoxazole and trimethoprim safe for dogs?
Answer
Sulfamethoxazole and trimethoprim are commonly used antibiotics in both human and veterinary medicine. These drugs can be used to treat a variety of bacterial infections in dogs, such as urinary tract infections, respiratory tract infections, and skin infections. However, like any medication, sulfamethoxazole and trimethoprim can have potential side effects and may not be safe for all dogs. Some dogs may be allergic to these antibiotics or may have underlying health conditions that make them more susceptible to adverse reactions. Sulfamethoxazole and trimethoprim should not be used in dogs with liver tissue damage, blood cell problems or in dogs that are dehydrated or at an increased risk for urinary stones. Additionally, these antibiotics should not be used in dogs that are known to be allergic to sulfonamides or have had an adverse reaction to these medications in the past.
2. How much sulfamethoxazole and trimethoprim should I give my dog?
Answer
In general, the standard dosage of sulfamethoxazole and trimethoprim for dogs is 30-45 mg/kg of body weight, given orally every 12-24 hours. The duration of treatment will depend on the type and severity of the infection being treated, but it is typically continued for at least 5-7 days. However, the dosage of sulfamethoxazole and trimethoprim that is appropriate for your dog will depend on several factors, including the dog's weight, age, and overall health, as well as the condition being treated.
3. What are the side effects of sulfamethoxazole-trimethoprim in dogs?
Answer
Sulfamethoxazole-trimethoprim is generally a safe and effective antibiotic when used appropriately in dogs. However, like all medications, it can cause side effects in some dogs. Common side effects of sulfamethoxazole-trimethoprim in dogs may include loss of appetite, vomiting, diarrhea, lethargy or weakness, skin rash or hives, itching or other signs of an allergic reaction, blood disorders (such as anemia or low platelet counts), kidney damage or dysfunction, and liver damage or dysfunction. In rare cases, sulfamethoxazole-trimethoprim can cause serious side effects, such as anaphylactic shock or a severe blood disorder called immune-mediated hemolytic anemia. If you notice any signs of a severe reaction, such as difficulty breathing, pale gums, or collapse, seek emergency veterinary care immediately.
4. Is sulfamethoxazole a strong antibiotic?
Answer
Sulfamethoxazole is a broad-spectrum antibiotic that is commonly used to treat bacterial infections in both humans and animals. When used in combination with trimethoprim, it is commonly referred to as "sulfamethoxazole-trimethoprim" or "SMZ-TMP." Sulfamethoxazole is generally considered to be a moderate to strong antibiotic and is effective against many different types of bacteria, including both gram-positive and gram-negative bacteria. However, like all antibiotics, they may not be effective against all types of bacteria, and some strains of bacteria may be resistant to their effects. The strength of an antibiotic depends on several factors, including the specific bacteria being targeted, the dosage and duration of treatment, and the individual patient's response to the medication. In some cases, sulfamethoxazole may be prescribed as a first-line treatment for certain types of bacterial infections, while in other cases, stronger or more targeted antibiotics may be necessary.
5. What kind of antibiotic is sulfamethoxazole for?
Answer
Sulfamethoxazole is a type of antibiotic that belongs to a class of drugs called sulfonamides. It works by inhibiting the growth and reproduction of bacteria, which helps to treat and prevent bacterial infections. Sulfamethoxazole is effective against a wide range of gram-positive and gram-negative bacteria, including some strains that are resistant to other antibiotics. It is commonly used to treat infections of the respiratory tract, urinary tract, skin, and soft tissues, as well as certain types of gastrointestinal infections. Sulfamethoxazole is often used in combination with another antibiotic called trimethoprim, which enhances its antibacterial effects and broadens its spectrum of activity.
6. How long does it take for sulfamethoxazole to work?
Answer
The length of time it takes for sulfamethoxazole to work in dogs can vary depending on the specific condition being treated and the severity of the infection. In general, sulfamethoxazole can start to improve symptoms within a few days of starting treatment, but it's necessary to complete the full course of treatment as prescribed by your veterinarian, even if your dog's symptoms improve. For uncomplicated urinary tract infections, sulfamethoxazole is typically prescribed for a course of 3-5 days. For more severe infections or infections that involve other parts of the body, such as the respiratory tract or skin, treatment may last for 7-14 days or longer.
7. Is sulfamethoxazole the same as amoxicillin?
Answer
No, sulfamethoxazole and amoxicillin are different antibiotics that belong to different classes of drugs and work in different ways to fight bacterial infections. Sulfamethoxazole is a sulfonamide antibiotic that works by inhibiting the growth and reproduction of bacteria, while amoxicillin is a penicillin-type antibiotic that works by blocking the formation of bacterial cell walls. While both sulfamethoxazole and amoxicillin are broad-spectrum antibiotics that can be used to treat a variety of bacterial infections, they are not interchangeable and are typically prescribed based on the specific type of infection being treated and the individual patient's needs. In some cases, a combination of different antibiotics may be prescribed to provide broader coverage against different types of bacteria.
Other Options
Swipe

Customers also boughtView All

Swipe
Customer Reviews
0 Star symbol Star symbol Star symbol Star symbol Star symbol
Based on 0 reviews
5 Star symbol
0
4 Star symbol
0
3 Star symbol
0
2 Star symbol
0
1 Star symbol
0
Be the first to write a review
PetPlus pricing activated
Instant savings for you

25% off coupon | Up to 40% off sitewide