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At a Glance
  • Treats Cushing's Disease in dogs and puppies weighing over 3.8 lbs
  • Improvement may be seen within several weeks
  • Available in 5 mg, 10 mg, 20 mg, 30 mg, 60 mg or 120 mg capsules (based on weight)

Vetoryl

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$74.71
$62.37 See Price in Cart with code CARE25 tooltip Why don't we show the price? Sometimes the manufacturers do not allow us to show our price. Don't worry; you'll be able to see the price in checkout before you decide to buy it.
Prescription Item

Prescription required.

Prescription item

Save $23 by joining PetPlus

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At a Glance
  • Treats Cushing's Disease in dogs and puppies weighing over 3.8 lbs
  • Improvement may be seen within several weeks
  • Available in 5 mg, 10 mg, 20 mg, 30 mg, 60 mg or 120 mg capsules (based on weight)
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About this product
1. How quickly does Vetoryl work?
Answer
Vetoryl starts working within 14 days. Vetoryl capsules are given to dogs and are used to treat Cushing’s disease. This particular medication is to be given to your dog orally and daily. The drug is to be given to your pet dog with food. You do not have to break or split the capsule while feeding it. Administered daily (or as prescribed by your vet), Vetoryl will begin its work within a couple of weeks (14 days).
2. What are the side effects of Vetoryl for dogs?
Answer
Side effects of Vetoryl for dogs include vomiting, diarrhea, weakness, and poor appetite. These side effects are likely to be seen within the first few days of the dosage. Prescription drugs for dogs or any other pets often lead to side effects; there is nothing unnatural about it. And these are mild symptoms or side effects that you need not worry about. However, do consult your vet if the side effects are there for a prolonged period. It is mostly to be safe, and see whether there is anything wrong with the dosage and if it needs to be changed in any way.
3. Are dogs with Cushing's in pain?
Answer
Yes, dogs with Cushing's are in pain. While it may not be a continuous painful experience, Cushing's disease leads to kidney and liver disease, high blood pressure, hair loss, and muscle weakness. All these combined can lead to a painful experience for your dog.
4. Can you just stop Vetoryl?
Answer
No, you cannot just stop Vetoryl. Even if your dog gets better, you have to finish the prescribed dosage. The treatment procedure requires you to finish the Vetoryl dosage, and you have to do so.
5. Why do dogs with Cushing's pant at night?
Answer
Dogs with Cushing’s pants at night because of two reasons: The abdominal cavity has an increased amount of fatty deposits or an increase in the liver size makes it difficult for the diaphragm to expand with ease, which leads to panting.
6. What happens if I don't treat my dog for Cushing's disease?
Answer
If you do not treat your dog for Cushing’s disease, it will develop bacterial infections. Slowly, but surely, vital functions of the body will start to fail and the condition will only keep on worsening.
7. What do you feed a dog with Cushing's disease?
Answer
You have to feed a high protein diet to a dog with Cushing’s disease. At the same time, you must also ensure a moderate quantity of fiber in the diet. Besides, the diet should not contain any fat content, or it must be as low as possible.
8. How does a dog with Cushing's feel?
Answer
A dog with Cushing’s feels tired. It has elevated levels of cortisol, which in turn leads to an increase in appetite. The dog also feels drowsy, and it can sense that its fur coat is losing quality. In some cases, dogs with Cushing's develop a bloated appearance.
9. Should I treat my old dog for Cushing's?
Answer
Yes, you should treat your old dog for Cushing’s disease. However, you have to take advice from a vet or licensed professional first. In many cases, the symptoms you observe might be there because of old age and not Cushing’s. Hence, before starting treatment, you should consult the vet.
10. Should I test my dog for Cushing's?
Answer
Yes, you should get your dog tested for Cushing’s syndrome. It is always a good idea to keep the symptoms in check and consult a vet when they are getting worse. So get your dog tested for Cushing’s disease if you are growing suspicious of the symptoms you have been observing. The vet will probably ask you to run multiple tests, just to make sure that they do not miss anything vital.
11. Does Cushing's disease in dogs come on suddenly?
Answer
No, Cushing’s disease in dogs does not come on suddenly. Cushing takes its time – like a year or so – to develop the symptoms. People often mistake these clinical signs as symptoms of aging. Hence, even when the symptoms are there and developing, people might mistake them for something else, or completely ignore them. And before owners know it, the Cushing’s disease in their dogs reaches an advanced state.
12. Do dogs with Cushing's need a special diet?
Answer
Yes, dogs with Cushing’s need a special diet. Cushing’s disease is caused due to the presence of excess cortisol in the body. Hence, the special diet needs to contain ingredients or content that can combat this excess presence of cortisol. You need to ensure the special diet has high digestible protein that helps to prevent muscle wasting, which is a major side effect of Cushing’s; low-fat since the dog with Cushing’s already has an elevated amount of fat content, it is best to provide a diet with low-fat content; and carbohydrates, since fibers are very important for the dog’s health. They should be present in the 8 to 17 percent range.
13. What should I do if I miss a dose of Vetoryl for my dog?
Answer
If you miss a dose of Vetoryl (trilostane) for your dog, you should give the missed dose as soon as you remember, unless it is almost time for the next scheduled dose. In that case, it is better to skip the missed dose and continue with the regular dosing schedule. However, it's important to stick to the prescribed dosing schedule as closely as possible to maintain consistent levels of medication in your dog's system.
14. Can Vetoryl affect dogs with liver disease?
Answer
Yes, but it must be controlled. Vetoryl (trilostane) is primarily metabolized in the liver, so it's important to use caution when administering this medication to dogs with liver disease. Vetoryl may not be suitable for dogs with severe liver disease or liver failure. Your veterinarian will assess your dog's liver function before prescribing Vetoryl, and they may recommend monitoring liver function throughout the course of treatment.
15. Can Vetoryl be given to dogs with kidney disease?
Answer
Vetoryl is primarily metabolized in the liver, and there is no direct effect on the kidneys. However, trilostane can cause dehydration and electrolyte imbalances, which can be harmful to dogs with kidney disease. Therefore, it's important to use caution when administering Vetoryl to dogs with kidney disease.
16. How often should I have my dog's blood cortisol levels checked while on Vetoryl?
Answer
During the initial stages of treatment, blood cortisol levels may be checked as frequently as every 2 weeks. Once the dosage has been stabilized and your dog's condition is under control, blood cortisol levels may be checked less frequently, such as every 3 to 6 months. However, your veterinarian may recommend more frequent or less frequent monitoring based on your dog's individual response to the medication, their age, and any other underlying health conditions they may have.
17. Can Vetoryl be given to dogs with diabetes?
Answer
Vetoryl can be used in dogs with diabetes, but it's important to use caution and closely monitor your dog's blood glucose levels while they are on the medication. Trilostane can lower cortisol levels in the body, which can cause a decrease in blood glucose levels. If your dog is diabetic and taking insulin, their insulin dosage may need to be adjusted while they are on Vetoryl to prevent hypoglycemia (low blood glucose levels).
18. Can Vetoryl be given to dogs with heart disease?
Answer
Dogs with cardiac problems can receive Vetoryl (trilostane), but it's crucial to exercise caution and keep a close eye on your dog's health while they're taking it. Dehydration and electrolyte imbalances are two adverse effects of trilostane that might aggravate existing cardiac issues. Before recommending Vetoryl, your veterinarian will examine the heart health of your dog, and they could advise continuing to keep an eye on it over the period of therapy.
19. Can Vetoryl be given to dogs with Cushing's syndrome caused by a pituitary tumor?
Answer
Yes, Vetoryl (trilostane) can be used to treat Cushing's syndrome caused by a pituitary tumor in dogs. Pituitary-dependent Cushing's syndrome is the most common form of the disease in dogs, and trilostane is often the treatment of choice. Trilostane works by inhibiting the production of cortisol, which is the hormone that is overproduced in dogs with Cushing's syndrome. By cutting down cortisol levels, trilostane can help alleviate the symptoms of the disease, such as excessive thirst and urination, increased appetite, and hair loss.
20. Can Vetoryl be given to dogs with hypothyroidism?
Answer
Yes, Vetoryl (trilostane) can be given to dogs with hypothyroidism, but it's important to use caution and closely monitor your dog's condition while they are on the medication. Trilostane can cause a decrease in thyroid hormone levels, so dogs with hypothyroidism may need to have their thyroid hormone levels monitored more frequently while taking Vetoryl.
21. Can Vetoryl be given to dogs with a history of seizures?
Answer
Yes, but with caution. Trilostane, the active ingredient in Vetoryl, has been associated with seizures in some dogs, especially at higher doses. Therefore, if your dog has a history of seizures, your veterinarian may recommend caution when using Vetoryl to treat Cushing's syndrome.
22. Can Vetoryl be given to dogs with high blood pressure?
Answer
Dogs with high blood pressure can take Vetoryl (trilostane), but it's vital to exercise caution and keep a close eye on your dog's blood pressure while they're taking it. Trilostane has the potential to lower blood pressure, which poses a risk to canines that already have high blood pressure.
23. Can Vetoryl be given to dogs with Addison's disease?
Answer
No, it cannot. Vetoryl (trilostane) is not typically used to treat Addison's disease in dogs, as it works by reducing the production of cortisol, the hormone that is overproduced in dogs with Cushing's syndrome. In contrast, dogs with Addison's disease have deficient cortisol production and require supplementation of cortisol or other hormones to manage the disease.

What is Vetoryl?

Vetoryl is used to treat dogs with hyperadrenocorticism (Cushing's Disease). Vetoryl (Trilostane) is a competitive inhibitor of the enzyme 3-beta-hydroxysteroid dehydrogenase used in dogs for the treatment of pituitary dependent Cushing's Disease and Cushing's Disease due to adrenocortical tumors. It may be necessary to wait at least one month after discontinuing Lysodren before starting treatment with Vetoryl. Vetoryl requires a prescription from your veterinarian.

Suitable for:

Dogs and Puppies > 3.8 lbs.

Benefits:

  • Treats Cushing's Disease in dogs and puppies weighing over 3.8 lbs
  • Improvement may be seen within several weeks
  • Available in 5 mg, 10 mg, 20 mg, 30 mg, 60 mg or 120 mg capsules (based on weight)

How does Vetoryl work?

Vetoryl controls the adrenal gland's excess production of cortisol, a hormone released into the bloodstream during times of stress.

Cautions:

Do not give this medication to dogs with kidney or liver disease. Vetoryl Capsules should not be given to dogs taking certain medications or dogs that are pregnant. Speak with your veterinarian about all medications your dog is taking, including over-the-counter medicines.

Brand Name:

Vetoryl

Generic Name:

Trilostane

What is the most important thing I should know about Vetoryl?

Vetoryl is a prescription medication FDA approved for veterinary use in the treatment of Cushing's Disease. Vetoryl is indicated for use in pituitary-dependent hyperadrenocorticism. Vetoryl also has a Minor Use designation for treatment of Cushing's Disease caused by adrenal tumors. Vetoryl is available as 5mg capsules, 10 mg capsules, 20 mg capsules, 30 mg capsules, 60 mg capsules and 120 mg capsules. The usual initial starting dose to treat Cushing's Disease in dogs is 1.0 to 3.0 mg/lb given once a day based on body weight and capsule size. For dogs weighing 3.8-10 lbs, give one 5 mg or 10 mg capsule once a day. For dogs weighing 10-22 lbs, give one 30 mg capsule once a day. For dogs weighing 22-44 lbs, give one 60 mg capsule. For dogs weighing 44-88 lbs, give one 120 mg capsule. For dogs weighing 88-132 lbs, give one 120 mg capsule and one 60 mg capsule, totaling 180 mg. For dogs weighing over 132 lbs, give the appropriate combination of capsules. Vetoryl should be given with food. After approximately 10 to 14 days, your pet will need to be re-examined and dosage adjustments may be required. Pets may require further re-examination at 30 days, 90 days, and every 3 months thereafter.

What should I discuss with my veterinarian before giving Vetoryl to my pet?

Tell your veterinarian if your pet has kidney or liver disease. Tell your veterinarian about any other medical problems or allergies your dog has now or has had in the past. Tell your veterinarian about any medications your dog is taking including over the counter products and nutritional supplements. Tell your veterinarian if your pet is pregnant, nursing, or if you plan to breed your dog.

How should Vetoryl be given?

Give this medication exactly as directed by your veterinarian. Give this medication with food. Do not open capsules and do not attempt to split or divide capsules. Wash your hands after use. Do not handle the capsules if you are pregnant or trying to become pregnant. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you.

What are the potential side effects of Vetoryl?

If any of the following serious side effects occur, stop giving Vetoryl and seek emergency veterinary medical attention; an allergic reaction (difficulty breathing; swelling of the lips, tongue or face; hives), severe depression, bloody diarrhea, collapse, or other severe reactions. Other less serious side effects such as unexpected decrease in appetite, vomiting, diarrhea, and lethargy may occur. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet.

What happens if I miss giving a dose of Vetoryl?

Give the missed dose as soon as you remember. However, if is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not give a double dose of the medication.

What happens if I overdose my pet on Vetoryl?

Seek emergency veterinary medical treatment. Symptoms of Vetoryl overdose may include lethargy, weakness, vomiting, or collapse.

What should I avoid while giving Vetoryl to my pet?

Do not give Vetoryl to dogs with kidney or liver disease. Do not give to pregnant or nursing dogs or dogs intended for breeding. Do not touch Vetoryl capsules if you are pregnant or trying to become pregnant.

What other drugs will affect Vetoryl?

Before giving Vetoryl, tell your veterinarian if your pet is also taking ACE inhibitors such as enalapril, potassium sparing diuretics such as spironolactone, ketoconazole, or potassium supplements. Talk to your veterinarian or pharmacist before giving any prescription or over the counter medicines or nutritional supplements.

See more

Vetoryl Directions:

  • Vetoryl is used to treat dogs with hyperadrenocorticism, also known as Cushing's Disease.
  • Vetoryl capsules should be given with food.
Tip:

Do not open capsules and do not attempt to split or divide capsule.

Vetoryl Dosage for Dogs/Puppies (weighing 3.8+ lbs):

Dogs/Puppies (weighing 3.8+ lbs):
Weight Dosage
3.8-10 lbs One 5 mg or 10 mg capsule daily
10-22 lbs One 20 mg or 30 mg capsule daily
22-44 lbs One 60 mg capsule daily
44-88 lbs One 120 mg capsule daily
88-132 lbs One 120 mg capsule plus one 60 mg capsule daily (180 mg total)
Over 132 lbs Administer the appropriate amount of capsules based on your dog's weight. Speak with your veterinarian to help you determine the correct dosage for your dog.
Vetoryl Dosage for Cats/Kittens:
Cats/Kittens
Do not use!
Vetoryl Dosage for Horses:
Horses
Do not use!
 

Vetoryl Ingredients:

Vetoryl 5 mg capsules:
Active Ingredients Amount
Trilostane 5 mg
Vetoryl 10 mg capsules:
Active Ingredients Amount
Trilostane 10 mg
Vetoryl 20 mg capsules:
Active Ingredients Amount
Trilostane 20 mg
Vetoryl 30 mg capsules:
Active Ingredients Amount
Trilostane 30 mg
Vetoryl 60 mg capsules:
Active Ingredients Amount
Trilostane 60 mg
Vetoryl 120 mg capsules:
Active Ingredients Amount
Trilostane 120 mg
Product Details
plus minus

What is Vetoryl?

Vetoryl is used to treat dogs with hyperadrenocorticism (Cushing's Disease). Vetoryl (Trilostane) is a competitive inhibitor of the enzyme 3-beta-hydroxysteroid dehydrogenase used in dogs for the treatment of pituitary dependent Cushing's Disease and Cushing's Disease due to adrenocortical tumors. It may be necessary to wait at least one month after discontinuing Lysodren before starting treatment with Vetoryl. Vetoryl requires a prescription from your veterinarian.

Suitable for:

Dogs and Puppies > 3.8 lbs.

Benefits:

  • Treats Cushing's Disease in dogs and puppies weighing over 3.8 lbs
  • Improvement may be seen within several weeks
  • Available in 5 mg, 10 mg, 20 mg, 30 mg, 60 mg or 120 mg capsules (based on weight)

How does Vetoryl work?

Vetoryl controls the adrenal gland's excess production of cortisol, a hormone released into the bloodstream during times of stress.

Cautions:

Do not give this medication to dogs with kidney or liver disease. Vetoryl Capsules should not be given to dogs taking certain medications or dogs that are pregnant. Speak with your veterinarian about all medications your dog is taking, including over-the-counter medicines.

Brand Name:

Vetoryl

Generic Name:

Trilostane

What is the most important thing I should know about Vetoryl?

Vetoryl is a prescription medication FDA approved for veterinary use in the treatment of Cushing's Disease. Vetoryl is indicated for use in pituitary-dependent hyperadrenocorticism. Vetoryl also has a Minor Use designation for treatment of Cushing's Disease caused by adrenal tumors. Vetoryl is available as 5mg capsules, 10 mg capsules, 20 mg capsules, 30 mg capsules, 60 mg capsules and 120 mg capsules. The usual initial starting dose to treat Cushing's Disease in dogs is 1.0 to 3.0 mg/lb given once a day based on body weight and capsule size. For dogs weighing 3.8-10 lbs, give one 5 mg or 10 mg capsule once a day. For dogs weighing 10-22 lbs, give one 30 mg capsule once a day. For dogs weighing 22-44 lbs, give one 60 mg capsule. For dogs weighing 44-88 lbs, give one 120 mg capsule. For dogs weighing 88-132 lbs, give one 120 mg capsule and one 60 mg capsule, totaling 180 mg. For dogs weighing over 132 lbs, give the appropriate combination of capsules. Vetoryl should be given with food. After approximately 10 to 14 days, your pet will need to be re-examined and dosage adjustments may be required. Pets may require further re-examination at 30 days, 90 days, and every 3 months thereafter.

What should I discuss with my veterinarian before giving Vetoryl to my pet?

Tell your veterinarian if your pet has kidney or liver disease. Tell your veterinarian about any other medical problems or allergies your dog has now or has had in the past. Tell your veterinarian about any medications your dog is taking including over the counter products and nutritional supplements. Tell your veterinarian if your pet is pregnant, nursing, or if you plan to breed your dog.

How should Vetoryl be given?

Give this medication exactly as directed by your veterinarian. Give this medication with food. Do not open capsules and do not attempt to split or divide capsules. Wash your hands after use. Do not handle the capsules if you are pregnant or trying to become pregnant. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you.

What are the potential side effects of Vetoryl?

If any of the following serious side effects occur, stop giving Vetoryl and seek emergency veterinary medical attention; an allergic reaction (difficulty breathing; swelling of the lips, tongue or face; hives), severe depression, bloody diarrhea, collapse, or other severe reactions. Other less serious side effects such as unexpected decrease in appetite, vomiting, diarrhea, and lethargy may occur. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet.

What happens if I miss giving a dose of Vetoryl?

Give the missed dose as soon as you remember. However, if is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not give a double dose of the medication.

What happens if I overdose my pet on Vetoryl?

Seek emergency veterinary medical treatment. Symptoms of Vetoryl overdose may include lethargy, weakness, vomiting, or collapse.

What should I avoid while giving Vetoryl to my pet?

Do not give Vetoryl to dogs with kidney or liver disease. Do not give to pregnant or nursing dogs or dogs intended for breeding. Do not touch Vetoryl capsules if you are pregnant or trying to become pregnant.

What other drugs will affect Vetoryl?

Before giving Vetoryl, tell your veterinarian if your pet is also taking ACE inhibitors such as enalapril, potassium sparing diuretics such as spironolactone, ketoconazole, or potassium supplements. Talk to your veterinarian or pharmacist before giving any prescription or over the counter medicines or nutritional supplements.

See more
How to use
plus minus

Vetoryl Directions:

  • Vetoryl is used to treat dogs with hyperadrenocorticism, also known as Cushing's Disease.
  • Vetoryl capsules should be given with food.
Tip:

Do not open capsules and do not attempt to split or divide capsule.

Vetoryl Dosage for Dogs/Puppies (weighing 3.8+ lbs):

Dogs/Puppies (weighing 3.8+ lbs):
Weight Dosage
3.8-10 lbs One 5 mg or 10 mg capsule daily
10-22 lbs One 20 mg or 30 mg capsule daily
22-44 lbs One 60 mg capsule daily
44-88 lbs One 120 mg capsule daily
88-132 lbs One 120 mg capsule plus one 60 mg capsule daily (180 mg total)
Over 132 lbs Administer the appropriate amount of capsules based on your dog's weight. Speak with your veterinarian to help you determine the correct dosage for your dog.
Vetoryl Dosage for Cats/Kittens:
Cats/Kittens
Do not use!
Vetoryl Dosage for Horses:
Horses
Do not use!
 
Ingredients
plus minus

Vetoryl Ingredients:

Vetoryl 5 mg capsules:
Active Ingredients Amount
Trilostane 5 mg
Vetoryl 10 mg capsules:
Active Ingredients Amount
Trilostane 10 mg
Vetoryl 20 mg capsules:
Active Ingredients Amount
Trilostane 20 mg
Vetoryl 30 mg capsules:
Active Ingredients Amount
Trilostane 30 mg
Vetoryl 60 mg capsules:
Active Ingredients Amount
Trilostane 60 mg
Vetoryl 120 mg capsules:
Active Ingredients Amount
Trilostane 120 mg
1. How quickly does Vetoryl work?
Answer
Vetoryl starts working within 14 days. Vetoryl capsules are given to dogs and are used to treat Cushing’s disease. This particular medication is to be given to your dog orally and daily. The drug is to be given to your pet dog with food. You do not have to break or split the capsule while feeding it. Administered daily (or as prescribed by your vet), Vetoryl will begin its work within a couple of weeks (14 days).
2. What are the side effects of Vetoryl for dogs?
Answer
Side effects of Vetoryl for dogs include vomiting, diarrhea, weakness, and poor appetite. These side effects are likely to be seen within the first few days of the dosage. Prescription drugs for dogs or any other pets often lead to side effects; there is nothing unnatural about it. And these are mild symptoms or side effects that you need not worry about. However, do consult your vet if the side effects are there for a prolonged period. It is mostly to be safe, and see whether there is anything wrong with the dosage and if it needs to be changed in any way.
3. Are dogs with Cushing's in pain?
Answer
Yes, dogs with Cushing's are in pain. While it may not be a continuous painful experience, Cushing's disease leads to kidney and liver disease, high blood pressure, hair loss, and muscle weakness. All these combined can lead to a painful experience for your dog.
4. Can you just stop Vetoryl?
Answer
No, you cannot just stop Vetoryl. Even if your dog gets better, you have to finish the prescribed dosage. The treatment procedure requires you to finish the Vetoryl dosage, and you have to do so.
5. Why do dogs with Cushing's pant at night?
Answer
Dogs with Cushing’s pants at night because of two reasons: The abdominal cavity has an increased amount of fatty deposits or an increase in the liver size makes it difficult for the diaphragm to expand with ease, which leads to panting.
6. What happens if I don't treat my dog for Cushing's disease?
Answer
If you do not treat your dog for Cushing’s disease, it will develop bacterial infections. Slowly, but surely, vital functions of the body will start to fail and the condition will only keep on worsening.
7. What do you feed a dog with Cushing's disease?
Answer
You have to feed a high protein diet to a dog with Cushing’s disease. At the same time, you must also ensure a moderate quantity of fiber in the diet. Besides, the diet should not contain any fat content, or it must be as low as possible.
8. How does a dog with Cushing's feel?
Answer
A dog with Cushing’s feels tired. It has elevated levels of cortisol, which in turn leads to an increase in appetite. The dog also feels drowsy, and it can sense that its fur coat is losing quality. In some cases, dogs with Cushing's develop a bloated appearance.
9. Should I treat my old dog for Cushing's?
Answer
Yes, you should treat your old dog for Cushing’s disease. However, you have to take advice from a vet or licensed professional first. In many cases, the symptoms you observe might be there because of old age and not Cushing’s. Hence, before starting treatment, you should consult the vet.
10. Should I test my dog for Cushing's?
Answer
Yes, you should get your dog tested for Cushing’s syndrome. It is always a good idea to keep the symptoms in check and consult a vet when they are getting worse. So get your dog tested for Cushing’s disease if you are growing suspicious of the symptoms you have been observing. The vet will probably ask you to run multiple tests, just to make sure that they do not miss anything vital.
11. Does Cushing's disease in dogs come on suddenly?
Answer
No, Cushing’s disease in dogs does not come on suddenly. Cushing takes its time – like a year or so – to develop the symptoms. People often mistake these clinical signs as symptoms of aging. Hence, even when the symptoms are there and developing, people might mistake them for something else, or completely ignore them. And before owners know it, the Cushing’s disease in their dogs reaches an advanced state.
12. Do dogs with Cushing's need a special diet?
Answer
Yes, dogs with Cushing’s need a special diet. Cushing’s disease is caused due to the presence of excess cortisol in the body. Hence, the special diet needs to contain ingredients or content that can combat this excess presence of cortisol. You need to ensure the special diet has high digestible protein that helps to prevent muscle wasting, which is a major side effect of Cushing’s; low-fat since the dog with Cushing’s already has an elevated amount of fat content, it is best to provide a diet with low-fat content; and carbohydrates, since fibers are very important for the dog’s health. They should be present in the 8 to 17 percent range.
13. What should I do if I miss a dose of Vetoryl for my dog?
Answer
If you miss a dose of Vetoryl (trilostane) for your dog, you should give the missed dose as soon as you remember, unless it is almost time for the next scheduled dose. In that case, it is better to skip the missed dose and continue with the regular dosing schedule. However, it's important to stick to the prescribed dosing schedule as closely as possible to maintain consistent levels of medication in your dog's system.
14. Can Vetoryl affect dogs with liver disease?
Answer
Yes, but it must be controlled. Vetoryl (trilostane) is primarily metabolized in the liver, so it's important to use caution when administering this medication to dogs with liver disease. Vetoryl may not be suitable for dogs with severe liver disease or liver failure. Your veterinarian will assess your dog's liver function before prescribing Vetoryl, and they may recommend monitoring liver function throughout the course of treatment.
15. Can Vetoryl be given to dogs with kidney disease?
Answer
Vetoryl is primarily metabolized in the liver, and there is no direct effect on the kidneys. However, trilostane can cause dehydration and electrolyte imbalances, which can be harmful to dogs with kidney disease. Therefore, it's important to use caution when administering Vetoryl to dogs with kidney disease.
16. How often should I have my dog's blood cortisol levels checked while on Vetoryl?
Answer
During the initial stages of treatment, blood cortisol levels may be checked as frequently as every 2 weeks. Once the dosage has been stabilized and your dog's condition is under control, blood cortisol levels may be checked less frequently, such as every 3 to 6 months. However, your veterinarian may recommend more frequent or less frequent monitoring based on your dog's individual response to the medication, their age, and any other underlying health conditions they may have.
17. Can Vetoryl be given to dogs with diabetes?
Answer
Vetoryl can be used in dogs with diabetes, but it's important to use caution and closely monitor your dog's blood glucose levels while they are on the medication. Trilostane can lower cortisol levels in the body, which can cause a decrease in blood glucose levels. If your dog is diabetic and taking insulin, their insulin dosage may need to be adjusted while they are on Vetoryl to prevent hypoglycemia (low blood glucose levels).
18. Can Vetoryl be given to dogs with heart disease?
Answer
Dogs with cardiac problems can receive Vetoryl (trilostane), but it's crucial to exercise caution and keep a close eye on your dog's health while they're taking it. Dehydration and electrolyte imbalances are two adverse effects of trilostane that might aggravate existing cardiac issues. Before recommending Vetoryl, your veterinarian will examine the heart health of your dog, and they could advise continuing to keep an eye on it over the period of therapy.
19. Can Vetoryl be given to dogs with Cushing's syndrome caused by a pituitary tumor?
Answer
Yes, Vetoryl (trilostane) can be used to treat Cushing's syndrome caused by a pituitary tumor in dogs. Pituitary-dependent Cushing's syndrome is the most common form of the disease in dogs, and trilostane is often the treatment of choice. Trilostane works by inhibiting the production of cortisol, which is the hormone that is overproduced in dogs with Cushing's syndrome. By cutting down cortisol levels, trilostane can help alleviate the symptoms of the disease, such as excessive thirst and urination, increased appetite, and hair loss.
20. Can Vetoryl be given to dogs with hypothyroidism?
Answer
Yes, Vetoryl (trilostane) can be given to dogs with hypothyroidism, but it's important to use caution and closely monitor your dog's condition while they are on the medication. Trilostane can cause a decrease in thyroid hormone levels, so dogs with hypothyroidism may need to have their thyroid hormone levels monitored more frequently while taking Vetoryl.
21. Can Vetoryl be given to dogs with a history of seizures?
Answer
Yes, but with caution. Trilostane, the active ingredient in Vetoryl, has been associated with seizures in some dogs, especially at higher doses. Therefore, if your dog has a history of seizures, your veterinarian may recommend caution when using Vetoryl to treat Cushing's syndrome.
22. Can Vetoryl be given to dogs with high blood pressure?
Answer
Dogs with high blood pressure can take Vetoryl (trilostane), but it's vital to exercise caution and keep a close eye on your dog's blood pressure while they're taking it. Trilostane has the potential to lower blood pressure, which poses a risk to canines that already have high blood pressure.
23. Can Vetoryl be given to dogs with Addison's disease?
Answer
No, it cannot. Vetoryl (trilostane) is not typically used to treat Addison's disease in dogs, as it works by reducing the production of cortisol, the hormone that is overproduced in dogs with Cushing's syndrome. In contrast, dogs with Addison's disease have deficient cortisol production and require supplementation of cortisol or other hormones to manage the disease.
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